Search Results - R. M. Shakhnovich

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  1. 1
    What is changing in the treatment of acute coronary syndrome in the Russian Federation?

    What is changing in the treatment of acute coronary syndrome in the Russian Federation? by S. A. Boytsov, B. G. Alekyan, R. M. Shakhnovich, V. I. Ganyukov

    Published 2023-01-01

    The work of the national network of vascular centers of the Russian Federation (RF), based on the Clinical recommendations of the Russian Society of Cardiology and the procedure for providing medical care to patients with cardiovascular diseases, has led to significant positive results in the treatm...

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  2. 2
    Cardiac shock care center — the next stage in the treatment of cardiogenic shock

    Cardiac shock care center — the next stage in the treatment of cardiogenic shock by S. A. Boytsov, R. S. Akchurin, D. V. Pevzner, R. M. Shakhnovich, M. Ya. Ruda

    Published 2019-11-01

    The key step in achieving a significant reduction  in mortality in patients  with myocardial infarction (MI) was the organization of a wide network of specialized PCI-centers that provide care for patients with acute coronary syndrome (ACS) on the 24/7 mode  in accordance   to clear protocols. Howev...

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  3. 3
    Cardiogenic shock — the current state of the problem

    Cardiogenic shock — the current state of the problem by S. A. Boytsov, R. S. Akchurin, D. V. Pevzner, R. M. Shakhnovich, M. Ya. Ruda

    Published 2019-11-01

    Today the incidence of cardiogenic shock (CS) among the patients with myocardial infarction (MI) is on average in 7-8%. Despite the fact that CS is not the most frequent complication of MI, it is the most common cause of death in this disease. The standard and new perspective treatment approaches ar...

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  4. 4
    Aspirin resistance in patients with acute coronary syndrome. Part 2

    Aspirin resistance in patients with acute coronary syndrome. Part 2 by N. S. Frolova, R. M. Shakhnovich, E. M. Kaznacheeva, O. V. Sirotkina, A. B. Dobrovolskyi

    Published 2011-04-01

    Aim. In patients with acute coronary syndrome (ACS), to investigate the prevalence of aspirin resistance, its clinical features, prognostic effects, and potential correction. Material and methods. The study included 100 ACS patients receiving aspirin. Aspirin resistance was diagnosed if at Day 7 of...

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  5. 5
    Aspirin resistance in patients with acute coronary syndrome. Part 1

    Aspirin resistance in patients with acute coronary syndrome. Part 1 by N. S. Frolova, R. M. Shakhnovich, E. M. Kaznacheeva, O. V. Sirotkina, A. B. Dobrovolsky

    Published 2010-12-01

    Aim. To evaluate the prevalence of aspirin resistance, its clinical features, potential solutions, and prognostic role in patients with acute coronary syndrome (ACS). Material and methods. The study included 51 patients with ACS and ST segment elevation (STEACS) and 49 ACS patients without ST segmen...

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  6. 6
    Prospects for a pharmacoinvasive strategy in ST-elevation myocardial infarction in the Russian Federation

    Prospects for a pharmacoinvasive strategy in ST-elevation myocardial infarction in the Russian Federation by V. E. Oleynikov, R. M. Shakhnovich, A. N. Yakovlev, R. M. Rabinovich, I. V. Avdeeva

    Published 2025-04-01

    In patients with ST-elevation myocardial infarction, primary percutaneous coronary intervention should be performed within 120 minutes after diagnosis if possible. Timely revascularization helps to preserve left ventricular function, minimizing myocardial damage, which subsequently reduces disabilit...

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  7. 7
    The echogenicity of atherosclerotic plaques in the carotid arteries in patients with acute coronary syndrome and its effect on the prognosis of cardiovascular events

    The echogenicity of atherosclerotic plaques in the carotid arteries in patients with acute coronary syndrome and its effect on the prognosis of cardiovascular events by D. A. Guchaeva, M. I. Tripoten, O. A. Pogorelova, G. I. Kheimets, R. M. Shakhnovich, T. V. Balakhonova

    Published 2019-06-01

    Some studies have shown that the echogenicity of atherosclerotic plaques (AP) in the carotid arteries (CA) plays an important role in evaluating the risk of cardiovascular events (CVE). The method of calculating the Gray Scale Median (GSM) is currently used to quantify the echogenicity of the CA pla...

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  8. 8
    The value of microvascular obstruction according to contrast-enhanced cardiac magnetic resonance imaging in assessing the prognosis of patients with acute ST-segment elevation myocardial infarction

    The value of microvascular obstruction according to contrast-enhanced cardiac magnetic resonance imaging in assessing the prognosis of patients with acute ST-segment elevation myoc... by M. A. Terenicheva, R. M. Shakhnovich, O. V. Stukalova, D. V. Pevzner, I. S. Yavelov, Yu. O. Shalaginova, S. K. Ternovoy

    Published 2024-04-01

    Aim. To study the relationship between the presence and size of microvascular obstruction (MVO) and the prognosis of patients with ST-segment elevation acute myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) within one year.Material and methods. The study inc...

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  9. 9
    EURASIAN CLINICAL GUIDELINES ON DIAGNOSIS AND TREATMENT OF ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION (STEMI)

    EURASIAN CLINICAL GUIDELINES ON DIAGNOSIS AND TREATMENT OF ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION (STEMI) by I. I. Staroverov, R. M. Shakhnovich, M. Yu. Gilyarov, A. L. Komarov, E. V. Konstantinova, E. P. Panchenko, I. S. Yavelov

    Published 2020-03-01

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  10. 10
    Early intravenous beta-blockers injection in patients with acute STEMI: the results of the Russian registry REGION-IM

    Early intravenous beta-blockers injection in patients with acute STEMI: the results of the Russian registry REGION-IM by T. S. Sukhinina, M. A. Terenicheva, R. G. Gulyan, R. M. Shakhnovich, O. V. Stukalova, O. A. Saygina, I. S. Yavelov, D. V. Pevsner

    Published 2024-12-01

    Aim. To study the features of the appointment of beta-blockers (BB) therapy in the early stages of acute myocardial infarction without ST segment elevation (nonSTEMI) in real clinical practice in the Russian Federation according to the REGION registry, to analyze the frequency and use cases of Intra...

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  11. 11
    Use of glycoprotein IIb/IIIa inhibitors in myocardial infarction in the Russian Federation, according to the Russian Registry of Acute Myocardial Infarction REGION-IM

    Use of glycoprotein IIb/IIIa inhibitors in myocardial infarction in the Russian Federation, according to the Russian Registry of Acute Myocardial Infarction REGION-IM by N. S. Kostritca, R. M. Rabinovich, R. M. Shakhnovich, I. S. Yavelov, R. G. Gulyan, Yu. K. Rytova, S. N. Tereschenko, A. D. Erlikh, D. V. Pevzner

    Published 2024-07-01

    Aim. To analyze the frequency, indications, and outcomes of using glycoprotein IIb/IIIa inhibitors in patients with acute myocardial infarction (AMI) in Russia based on data from a multicenter registry.Material and methods. This work is part of the REGION-MI (Russian Registry of Acute Myocardial Inf...

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  12. 12
    Non-immunogenic staphylokinase in patients with massive intermediate-high risk pulmonary embolism: protocol of the FORPE-2 multicenter, double-blind, randomized, placebo-controlled trial

    Non-immunogenic staphylokinase in patients with massive intermediate-high risk pulmonary embolism: protocol of the FORPE-2 multicenter, double-blind, randomized, placebo-controlled... by S. N. Tereshchenko, E. B. Yarovaya, S. G. Leontiev, I. S. Yavelov, R. M. Shakhnovich, A. D. Erlikh, T. M. Uskach, D. V. Duplyakov, V. A. Kutsenko, O. E. Ivlev, A. G. Soplenkova, A. M. Semenov, M. P. Semenov, S. V. Ivanov, S. S. Markin

    Published 2025-03-01

    Aim. To evaluate the efficacy and safety of single bolus administration of non-immunogenic staphylokinase in comparison with placebo in patients with intermediatehigh risk pulmonary embolism (PE) within the FORPE-2 clinical trial.Material and methods. Non-immunogenic staphylokinase has high thrombol...

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  13. 13
    Particularities of the course and treatment of non-ST elevation acute myocardial infarction: data from the REGION-IM registry

    Particularities of the course and treatment of non-ST elevation acute myocardial infarction: data from the REGION-IM registry by S. A. Boytsov, R. M. Shakhnovich, S. N. Tereshchenko, A. D. Erlikh, D. V. Pevzner, R. G. Gulyan, Yu. K. Rytova, D. V. Khegya, A. A. Khafizov, T. V. Kuzmicheva, A. N. Potapova, E. Yu. Gaskova, N. A. Medvedeva, T. A. Gorozhankina, M. A. Stavtseva, I. V. Romakh

    Published 2024-05-01

    Aim. To characterize patients with acute non-ST elevation myocardial infarction (NSTEMI) hospitalized in Russian hospitals, study their anamnestic, demographic and clinical characteristics, treatment features and hospital outcomes, as well as compare data from previous Russian and foreign registries...

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  14. 14
    Differentiated approach in diagnostics, diagnosis formulation, case management and statistical accounting of type 2 myocardial infarction (Position Paper)

    Differentiated approach in diagnostics, diagnosis formulation, case management and statistical accounting of type 2 myocardial infarction (Position Paper) by O. V. Averkov, O. L. Barbarash, S. A. Boytsov, E. Yu. Vasilieva, O. M. Drapkina, A. S. Galyavich, M. Yu. Gilyarov, O. V. Zayratiants, L. V. Kakturskiy, Yu. A. Karpov, O. D. Mishnev, N. N. Nikulina, O. O. Orekhov, I. V. Samorodskaya, G. N. Soboleva, S. N. Cherkasov, R. M. Shakhnovich, A. S. Shilova, E. V. Shlyakhto, A. V. Shpektor, I. S. Yavelov, S. S. Yakushin

    Published 2019-07-01

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  15. 15
    Place of Prasugrel, P2Y12 receptor antagonist, in an early invasive treatment of patients with acute coronary syndrome (according to the results of multicenter randomized controlled trial ISAR-REACT 5)

    Place of Prasugrel, P2Y12 receptor antagonist, in an early invasive treatment of patients with acute coronary syndrome (according to the results of multicenter randomized... by S. N. Tereshchenko, M. G. Glezer, S. A. Abugov, O. V. Averkov, S. I. Antipov, A. S. Galyavich, M. Yu. Gilyarov, D. V. Duplyakov, A. A. Efremushkina, D. A. Zateyshchikov, V. V. Ivanenko, E. D. Kosmacheva, O. V. Krestyaninov, Yu. M. Lopatin, E. P. Panchenko, V. V. Ryabov, E. V. Samokhvalov, I. I. Staroverov, S. A. Ustyugov, A. V. Khripun, S. V. Shalaev, R. M. Shakhnovich, I. S. Yavelov, A. N. Yakovlev, S. S. Yakushin

    Published 2019-11-01

    The conclusion of the Expert Council reports an agreement on the place of the P2Y12 receptor blocker prasugrel in the early invasive treatment of patients with acute coronary syndrome ACS, according to the results of the multicenter randomized controlled study ISAR-REACT 5. Prasugrel should be consi...

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  16. 16
    Advanced results of Fortelyzin® use in the FRIDOM1 study and real clinical practice

    Advanced results of Fortelyzin® use in the FRIDOM1 study and real clinical practice by V. A. Markov, D. V. Duplyakov, S. L. Konstantinov, G. V. Klein, S. B. Aksentiev, D. Yu. Platonov, E. V. Vyshlov, Е. A. Ponomarev, R. M. Rabinovich, E. L. Makarov, E. V. Kulibaba, D. S. Yunevich, O. V. Kritskaya, E. A. Baranov, O. B. Talibov, V. A. Kutsenko, A. A. Orlovsky, N. L. Vyazova, A. G. Koledinsky, A. M. Semenov, M. P. Semenov, E. B. Yarovaya, T. M. Uskach, R. M. Shakhnovich, S. N. Tereshchenko, S. S. Markin

    Published 2022-09-01

    Aim. To study the effectiveness of Fortelyzin® in subgroups with different body weights in patients with ST-segment elevation acute myocardial infarction (STEMI) in the FRIDOM1 study and real clinical practice.Material and methods. Fortelyzin® was administered in a single-bolus dose of 15 mg over 10...

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  17. 17
    2020 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation

    2020 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation by O. L. Barbarash, D. V. Duplyakov, D. A. Zateischikov, E. P. Panchenko, R. M. Shakhnovich, I. S. Yavelov, A. N. Yakovlev, S. A. Abugov, B. G. Alekyan, M. V. Arkhipov, E. Yu. Vasilieva, A. S. Galyavich, V. I. Ganyukov, S. R. Gilyarevskyi, E. P. Golubev, E. Z. Golukhova, N. A. Gratsiansky, Yu. A. Karpov, E. D. Kosmacheva, Yu. M. Lopatin, V. A. Markov, N. N. Nikulina, D. V. Pevzner, N. V. Pogosova, A. V. Protopopov, D. V. Skrypnik, S. N. Tereshchenko, S. A. Ustyugov, A. V. Khripun, S. V. Shalaev, V. A. Shpektor, S. S. Yakushin

    Published 2021-05-01

    Endorsed by: Research and Practical Council of the Ministry of Health of the Russian Federation.

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  18. 18
    2024 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation electrocardiogram

    2024 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation electrocardiogram by O. V. Averkov, G. K. Harutyunyan, D. V. Duplyakov, E. V. Konstantinova, N. N. Nikulina, R. M. Shakhnovich, I. S. Yavelov, A. N. Yakovlev, S. A. Abugov, B. G. Alekyan, D. M. Aronov, M. V. Arkhipov, O. L. Barbarash, S. A. Boytsov, M. G. Bubnova, T. V. Vavilova, E. Yu. Vasilyeva, A. S. Galyavich, V. I. Ganyukov, S. R. Gilyarevsky, E. P. Golubev, E. Z. Golukhova, D. A. Zateyshchikov, Yu. A. Karpov, E. D. Kosmacheva, Yu. M. Lopatin, V. A. Markov, E. V. Merkulov, N. A. Novikova, E P. Panchenko, D. V. Pevzner, N. V. Pogosova, D. M. Prasol, A. V. Protopopov, D. V. Skrypnik, R. S. Tarasov, S. N. Tereshchenko, S. A. Ustyugov, A. V. Khripun, E. A. Tsebrovskaya, S. V. Shalaev, E. V. Shlyakhto, A. V. Shpektor, S. S. Yakushin

    Published 2025-07-01

    Russian Society of Cardiology (RSC)With the participation of: the Association of Cardiovascular Surgeons, the Russian Society of Emergency Medical Care, the Russian Association of Ultrasound Diagnostics Specialists in Medicine (RASUDM)Approved by the Research and Practical Council of the Ministry of...

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  19. 19
    2024 Clinical practice guidelines for Acute myocardial infarction with ST segment elevation electrocardiogram

    2024 Clinical practice guidelines for Acute myocardial infarction with ST segment elevation electrocardiogram by O. V. Averkov, G. K. Harutyunyan, D. V. Duplyakov, E. V. Konstantinova, N. N. Konstantinova, R. M. Shakhnovich, I. S. Yavelov, A. N. Yakovlev, S. A. Abugov, B. G. Alekyan, D. M. Aronov, M. V. Arkhipov, O. L. Barbarash, S. A. Boytsov, M. G. Bubnova, T. N. Vavilova, E. Yu. Vasilyeva, A. S. Galyavich, V. I. Ganyukov, S. R. Gilyarevsky, E. P. Golubev, E. Z. Golukhova, D. A. Zateyshchikov, Yu. A. Karpov, E. D. Kosmacheva, Yu. M. Lopatin, V. A. Markov, E. V. Merkulov, N. A. Novikova, E. P. Panchenko, D. V. Pevzner, N. V. Pogosova, D. M. Prasol, A. V. Protopopov, D. V. Skrypnik, R. S. Tarasov, S. N. Tereshchenko, S. A. Ustyugov, A. V. Khripun, E. A. Tsebrovskaya, S. V Shalaev, E. V. Shlyakhto, A. V Shpektor, S. S. Yakushin

    Published 2025-04-01

    Russian Society of Cardiology (RSC)With the participation of: the Association of Cardiovascular Surgeons, the Russian Society of Emergency Medical Care, the Russian Association of Ultrasound Diagnostics Specialists in Medicine (RASUDM)Approved by the Research and Practical Council of the Ministry of...

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  20. 20
    Non-immunogenic staphylokinase — a thrombolytic agent in the treatment of massive pulmonary embolism: results of the FORPE clinical trial

    Non-immunogenic staphylokinase — a thrombolytic agent in the treatment of massive pulmonary embolism: results of the FORPE clinical trial by A. I. Kirienko, S. G. Leontyev, E. B. Yarovaya, S. I. Konstantinov, B. B. Orlov, Imad Meray, D. V. Duplyakov, V. E. Oleynikov, E. Yu. Vasilyeva, E. A. Ponomarev, S. A. Pribylov, A. G. Komarova, V. V. Bobkov, R. M. Rabinovich, G. V. Klein, Z. S. Shogenov, Yu. V. Karabach, V. N. Zolkin, V. V. Kulabukhov, V. V. Kashtalap, K. A. Linev, G. I. Stryabkova, N. V. Yasnopolskaya, V. Yu. Tolmacheva, Zh. Yu. Chefranova, Yu. A. Lykov, E. S. Panina, N. V. Solovieva, E. V. Rybin, N. V. Furman, E. V. Kulibaba, V. V. Makukhin, A. G. Koledinsky, I. S. Mullova, N. A. Cherepanova, T. V. Pavlova, P. P. Savvinova, I. A. Libov, A. S. Igoshin, I. Yu. Bogomazov, T. B. Pecherina, L. O. Lyudnev, P. N. Vlasov, I. V. Avdeeva, D. B. Maksimov, E. V. Komissarova, V. S. Ivanov, N. L. Vyazova, E. V. Vyshlov, D. S. Kurtasov, V. A. Kutsenko, O. E. Ivlev, A. G. Soplenkova, S. N. Tereshchenko, I. S. Yavelov, R. M. Shakhnovich, A. D. Erlikh, O. B. Talibov, A. M. Semenov, M. P. Semenov, S. V. Ivanov, Yu. A. Romashova, V. V. Beregovykh, A. I. Archakov, S. S. Markin

    Published 2024-12-01

    Aim. To assess the safety and efficacy of a single intravenous bolus of non-immunogenic staphylokinase compared with alteplase in patients with massive pulmonary embolism and hemodynamic instability. Non-immunogenic staphylokinase is a modified recombinant staphylokinase with low immunogenicity, hig...

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