Search Results - Qingfeng Zhang

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  1. 1

    Exploring the Determinants of Users’ Intention to Use Augmented Reality in Craftsmanship-Oriented Intangible Cultural Heritage Games by Shiwen Lai, Qingfeng Zhang

    Published 2025-07-01

    Augmented Reality (AR) technology has improved the dissemination of cultural heritage. The existing research predominantly focuses on technical presentation and user experience. However, the underlying mechanisms driving user adoption remain underexplored, especially in craftsmanship-related intangi...

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  2. 2

    STK11 mutation impacts CD1E expression to regulate the differentiation of macrophages in lung adenocarcinoma by Qingfeng Zhang, Juan Feng, Kui Liu, Xiaoyan Yang, Yun Huang, Bo Tang

    Published 2023-07-01

    Abstract Background The deficiency of serine/threonine protein kinase 11 (STK11), one of the most common tumor suppressor genes in non‐small‐cell lung cancer, is a crucial player in tumor immune microenvironment regulation. This study attempted to unveil how mutated STK11 impact the differentiation...

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  3. 3

    SNP variation landscape of BMP15 gene from 75 global sheep breeds and their genetic effect on lambing traits by Peiyao Liu, Chunna Cao, Chunna Cao, Xiangding Wang, Kewei Li, Ebadu Areb, Ran Li, Qingfeng Zhang, Chuanying Pan, Xianyong Lan

    Published 2025-07-01

    IntroductionBone morphogenetic protein 15 (BMP15) is a pivotal regulator of reproductive performance. This study aimed to investigate genetic variations in the sheep BMP15 gene and their role in lambing traits.MethodsWhole-genome sequencing was performed on 2,409 individuals from 75 global sheep bre...

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  4. 4

    Directed evolution of novel AAV variants using the MCMS library for enhanced CNS tropism and reduced liver targeting in mice by Qingkai Song, Jiamei Wu, Qingfeng Zhang, Shufang Wu, Xin Luo, Mengmeng Xu, Yinxia Xu, Gang Wang, Hang Yu, Hui Chen, Zhike Lu, Lijia Ma

    Published 2025-09-01

    Systemic delivery of adeno-associated virus serotype 9 (AAV9) to the central nervous system (CNS) is insufficient due to hindrance from the tight junctions of the blood-brain barrier (BBB). While peptide-display-based AAV engineering has advanced CNS-targeting capsid development, traditional strateg...

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