Risultati della ricerca - Qian Han
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The clinical and genetic profiles of spinal muscular atrophy with respiratory distress type 1 and identification of a novel mutation in IGHMBP2 in China
Pubblicazione 2025-07-01TestoBackgroundSpinal muscular atrophy with respiratory distress type 1 (SMARD1, OMIM #604320) is a rare autosomal recessive hereditary degenerative motor neuron disease caused by mutations in IGHMBP2. There is a lack of data from China. This study investigated the clinical characteristics and genetic ro...
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Miniaturized dual-band bandpass filter with closely spaced passbands and wide stopband
Pubblicazione 2025-07-01TestoThis work presents a new miniaturized dual-band bandpass filter (BPF) featuring closely spaced passbands and wide stopband performance. The filter is designed on a slots-loaded substrate integrated waveguide (SIW) cavity fed by microstrip line. By introducing a longitudinal rectangular slot at the c...
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Delayed Viral Clearance Accompanied by Early Impaired Humoral and Virus-Specific T-Cell Response in Patients with Coronavirus Disease 2019 and Interstitial Lung Disease
Pubblicazione 2025-06-01TestoObjectives: Patients with interstitial lung disease (ILD) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are at high risk of severe coronavirus disease 2019. It is unclear whether anti-viral cellular and humoral immunity is impacted in patients with ILD in the presence of...
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Porcine reproductive and respiratory syndrome virus 2 hijacks CMA-mediated lipolysis through upregulation of small GTPase RAB18.
Pubblicazione 2024-04-01TestoRAB GTPases (RABs) control intracellular membrane trafficking with high precision. In the present study, we carried out a short hairpin RNA (shRNA) screen focused on a library of 62 RABs during infection with porcine reproductive and respiratory syndrome virus 2 (PRRSV-2), a member of the family Art...
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