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    Nuclear receptors in metabolism and diseases: Mechanistic and therapeutic insights

    Nuclear receptors in metabolism and diseases: Mechanistic and therapeutic insights by Chen-Ying Zhu, Pei-Han Yu, Qi Sun, De-Fei Hong, Chang Yang, Hua Naranmandura

    Published 2025-08-01

    Nuclear receptors (NRs) are ligand-activated transcription factors that function as metabolic sensors, integrating endogenous and xenobiotic signals to regulate gene networks controlling metabolism, immunity, and cellular homeostasis. Recent studies elucidated the pivotal roles of NRs (e.g., PPARs,...

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