Search Results - Pei Lin
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Probing a one-loop quantum-corrected Schwarzschild spacetime with precessing and periodic motion by Ze-Lin Wei, Jing Zhang, Yi Xie, Pei-Lin Yin
Published 2025-06-01Abstract We investigate the bound orbits of a test timelike particle around the Schwarzschild spacetime with one-loop quantum correction in this work. After obtaining the marginally bound orbit and innermost stable circular orbit numerically, we find that both of their radii decrease with the rescal...
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Decoding MHC loss: Molecular mechanisms and implications for immune resistance in cancer by Pei Lin, Yunfan Lin, Xu Chen, Xinyuan Zhao, Li Cui
Published 2025-07-01Abstract Loss or downregulation of major histocompatibility complex (MHC) molecules represents a key mechanism by which tumours escape immune recognition and acquire resistance to immunotherapeutic interventions. This review focuses on the central regulatory pathways. These includes transcriptional...
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Numerical modeling and wind tunnel experimental study of pollutant dispersion in coastal continent by Meng-yu Yao, Zhi-xiang Liu, Pei-lin Xiao, Dong Xie
Published 2025-10-01Coastal areas are preferred for nuclear power plants due to the availability of seawater for cooling. However, siting also requires evaluating radiation doses to the environment and public during normal operation and potential accidents. This study examines how thermal differences and coastal meteor...
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Microarray Analysis Reveals Sepsis Is a Syndrome with Hyperactivity of TH17 Immunity, with Over-Presentation of the Treg Cell Cytokine TGF-β by Yu-Ju Chen, Jang-Jih Lu, Chih-Pei Lin, Wan-Chung Hu
Published 2025-06-01Currently, there are two major theories regarding the pathogenesis of sepsis: hyperimmune and hypoimmune. The hyperimmune theory suggests that a cytokine storm causes the symptoms of sepsis. On the contrary, the hypoimmune theory suggests that immunosuppression causes the manifestations of sepsis. B...
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Accurate detection of low concentrations of microplastics in soils via short-wave infrared hyperspectral imaging by Huan Chen, Taesung Shin, Bosoon Park, Kyoung Ro, Changyoon Jeong, Hwang-Ju Jeon, Pei-Lin Tan
Published 2025-07-01This study evaluated the effectiveness of coupling machine learning algorithms with short-wave infrared hyperspectral imaging in detecting two types of microplastics - polyamide and polyethylene - with the maximum particle sizes of 50 and 300 μm, respectively, across three concentration ranges (0.0...
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An important call: Suggestion of using IL-10 as therapeutic agent for COVID-19 with ARDS and other complications by Li-Jane Shih, Chun-Chun Yang, Min-Tser Liao, Kuo-Cheng Lu, Wan-Chung Hu, Chih-Pei Lin
Published 2023-12-01The global coronavirus disease 2019 (COVID-19) pandemic has a detrimental impact on public health. COVID-19 usually manifests as pneumonia, which can progress into acute respiratory distress syndrome (ARDS) related to uncontrolled TH17 immune reaction. Currently, there is no effective therapeutic ag...
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Automated Whole-Liver Fat Quantification with Magnetic Resonance Imaging-Derived Proton Density Fat Fraction Map: A Prospective Study in Taiwan by Chih-Horng Wu, Kuang-Chen Yen, Li-Ying Wang, Ping-Lun Hsieh, Wei-Kai Wu, Pei-Lin Lee, Chun-Jen Liu
Published 2025-07-01Background/Aims : Magnetic resonance imaging (MRI) with a proton density fat fraction (PDFF) sequence is the most accurate, noninvasive method for assessing hepatic steatosis. However, manual measurement on the PDFF map is time-consuming. This study aimed to validate automated whole-liver fat quanti...
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Unveiling the metabolic fate of drugs through metabolic reaction-based molecular networking by Haodong Zhu, Xupeng Tong, Qi Wang, Aijing Li, Zubao Wu, Qiqi Wang, Pei Lin, Xinsheng Yao, Liufang Hu, Liangliang He, Zhihong Yao
Published 2025-06-01Effective annotation of in vivo drug metabolites using liquid chromatography-mass spectrometry (LC–MS) remains a formidable challenge. Herein, a metabolic reaction-based molecular networking (MRMN) strategy is introduced, which enables the “one-pot” discovery of prototype drugs and their metabolites...
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Induction and characterization of polyploids from seeds of Rhododendron fortunei Lindl. by Lan MO, Jun-hao CHEN, Fei CHEN, Qiang-wei XU, Zai-kang TONG, Hua-hong HUANG, Ren-hui DONG, Xiong-zhen LOU, Er-pei LIN
Published 2020-08-01Most Rhododendron species are ornamental flowering species widely distributed in Asia, North America, and West Europe. Rhododendron fortunei, one of the endemic Rhododendron species in China, has beautiful flowers with bright colors and is being exploited to meet the needs of the flower market. Poly...
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Adipose-derived mesenchymal stem cell-supported ciprofloxacin therapy effectively protects the kidney parenchyma and functional integrity against acute pyelonephritis damage in rod... by Chih-Chao Yang, Ya Yue, Pei-Lin Shao, Ben-Chung Cheng, Tsuen-Wei Hsu, Yi-Ling Chen, Sheung-Fat Ko, Hon-Kan Yip, Mel S. Lee
Published 2025-06-01This study revealed that adipose-derived mesenchymal stem cell-facilitated ciprofloxacin therapy effectively protected the kidney parenchyma and functional integrity against acute pyelonephritis damage in rodents. In vitro studies revealed that adipose-derived mesenchymal stem cell-derived media sig...
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11
Delivery of LOXL1-AS1-siRNAs using targeting peptide-engineered extracellular vesicles with focused ultrasound to suppress medulloblastoma metastasis by Anh Duy Do, Shing-Shung Chu, Le Hien Giang, Pei-Lin Huang, Yu-Ling Lin, Che-Chang Chang, Tai-Tong Wong, Shian-Ying Sung, Chia-Ling Hsieh
Published 2025-06-01Abstract Background Metastasis of medulloblastomas (MBs) is difficult to treat and remains the primary cause of death in children with this brain tumor. Current treatment focuses on radiotherapy to limit metastatic recurrence and maintain survival, but this may cause long-term neurocognitive deficit...
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Enhancing Neurocognitive Health via Activity, Nutrition and Cognitive Exercise (ENHANCE): A Randomized Controlled Trial by Li‐Ning Peng, Pei‐Lin Lee, Kun‐Hsien Chou, Wei‐Ju Lee, Ching‐Po Lin, Chih‐Wen Chang, Chih‐Kuang Liang, Chih‐Ping Chung, Fei‐Yuan Hsiao, Liang‐Kung Chen
Published 2025-06-01ABSTRACT Background While multidomain interventions show promise for promoting healthy aging, their impact on brain structure remains unclear. This randomized controlled trial (ENHANCE) assessed the efficacy of a 12‐month group‐based multidomain intervention on brain structure and function in commun...
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