Search Results - O. V. Smirnova

A study of the peculiarities of clinical manifestations and immunity in patients with chronic myeloid leukemia, depending on the stage of disease was made. In patients at admission were more prevalen t shortness of breath, palpitations, lymphadenopathy, hepatomegaly, splenomegaly, hemorrhagic manife...

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Abstract. Supervision over 70 patients with acute no lymphoblastic leukemia and 65 patients with acute lymphoblastic leukemia, admitted in hematological department of Regional clinical hospital of № 1 of Krasnoyarsk city were made. It was established, that at a combination of G6PDG activity in blood...

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Abstract. In this study, we have identified functional features of immune system cells in patients with acute lymphoblastic leukemia (ALL), depending on clinical stage of the disease. At all stages of the disease, the patients developed T-cell immunodeficiency. A decrease in T lymphocyte scores and...

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Stomach cancer is in the top ten in terms of prevalence and ranks 4th in terms of causes of death worldwide. The most common and most aggressive variant of gastric cancer is adenocarcinoma. The monocytic link of immunity provides the main line of the body's fight against malignant cells, while...

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Aim. To study the content of cytokines in the blood serum of patients with obstructive jaundice of gallstone origin before and after surgical treatment, depending on the development of postoperative complications.Materials and methods. The treatment group consisted of 70 patients with the diagnosis...

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When the body is infected with the bacterium Helicobacter pylori, a cytokine cascade is launched, which plays a key role in the progression of chronic inflammatory and destructive processes in the gastric mucosa. Thus, the secretion of a number of cytokines is stimulated, which in turn contribute to...

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Conflicting data on the role of the metabolic syndrome (MS) in the development of hepatocellular carcinoma (HCC) require studies on the influence of molecular factors that are important in the development of HCC in MS, which was the goal of our review. Publications (scientific articles and reviews)...

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Chronic rhinosinusitis (CRS) is a disease which manifests with inflammation of the upper respiratory tract. Two main phenotypes can be distinguished in CRS: a clinical form with polypous tissue, and a clinical variant without polyposis. With regard of increased cytokine concentrations, the inflammat...

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Abstract. We examined metabolic status of blood lymphocytes in forty-four patients with chronic myeloid leukemia (CML), and in fifty-seven patients with chronic lymphoid leukemia (CLL). The most pronounced changes of enzyme activities are found in blood lymphocytes of CML and CLL patients during ter...

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The aim of present work was to study some activation features of neutrophilic granulocytes from peripheral blood of the patients with G type of multiple myeloma (MM), as depending on clinical stage of the disorder. In this study, a number of parameters were evaluated, as follows: time dynamics of th...

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Abstract. We examined immunological state in 100 patients with acute non-lymphoblastic leukemia (ANLL, M4), and in 73 cases of acute lymphoblastic leukemia (ALL, common variant). The most expressed disturbances of immune status in ANLL patients were revealed during relapses, and in patients with ALL...

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Abstract. We studied immunological state and activity of enzymes in blood lymphocytes from the patients at different stages of acute lymphoblastic leukemia. We have revealed that immune state in all the patients was characterized by decreased contents of T-lymphocytes. Upon first attack of the disea...

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Аbstract. The purpose of study was to evaluate some characteristics of immune state in the patients with acute non-differentiated leukemia (ANLL) and acute lymphoblastic leukemia (ALL), and to detect interrelations between the features of immune state and their dependencies on disease stage and quan...

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Chronic rhinosinusitis (CRS) is a disease caused by inflammation of the paranasal sinuses and its mucous membrane lasting for more than 4 weeks continuously. The aim of our study was to examine the main pathophysiological features of chronic IgE-mediated rhinosinusitis of bacterial etiology accordin...

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Theoretical studies of the interactions of an oxygen molecule with the surface of a solid phase are of great importance for understanding the mechanisms of reactions involving oxygen on a solid surface. In this work, the spatial and electronic structure of oxygen defects and nitrogen impurity cente...

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The influence of different beta-blockers (anaprilin, atenolol, nebilet) on the level of 11-oxycorticosteroids in rats with experimental chronic heart failure.

Chronic gastritis is the most common disease of gastro-intestinal tract. Precancerous potential is among most important epidemiological features of chronic gastritis. Immune system plays a distinct role in transformation from precancerous state to malignancy. In this context, the aim of our work was...

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Aim. A study of monocyte chemiluminescent activity at variant stages of gastric cancer.Materials and methods. The study enrolled 90 gastric cancer patients and 70 healthy donors. Spontaneous and induced chemiluminescence in monocytes was assessed for 90 min with a “BLM 3607” 36-channel chemiluminesc...

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The experimental results obtained in the study on the possibility of sensitizing titanium dioxide (polymorphic anatase phase) to the visible region of the spectrum by doping and co-doping with impurities of non-metals in order to create effective photocatalysts for the decomposition of organic comp...

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Summary Aim of study: To study the vibration sensitivity (VS) in rheumatoid arthritis (RA) depending on the clinical peculiarities of the disease. Material and methods: The study included 67pts (M:F=7:60) with reliable RA (ARA criteria, 1987). 55 out of 67 pts were positive on rheumatoid factor (RF)...

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