Search Results - O. S. Polunina

Early diagnosis of aortic stenosis may begin with the identification of left ventricular hypertrophy by two-dimensional Doppler echocardiography. For aortic stenosis characterized by concentric left ventricular remodeling, when the index for normal left ventricular mass index increased relative wall...

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In this paper we have carried out the diagnosis of the damage of the vascular endothelium in patients with ischemic heart disease (IHD) based on the study of gene of endothelial nitric oxide synthase polymorphism, the condition of vasoregulating function of endothelium, endothelin-1 and the level of...

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We have studied indicators of oxidative stress (carbonyl derivatives and TBA-active products) and antioxidant protection (activity of superoxide dismutase) at infertile (140) and fertile (140) patients with chronic prostatitis on a background of sexually transmitted infections (STIs). The increase i...

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We have examined 35 patients with bronchial asthma (BA), 35 patients with ischemic heart disease (IHD), 35 patients with arterial hypertension (AH), 40 patients with a combination of BA+IHD and 40 patients with a combination of BA+AH. To assess the state of vascular endothelium in the laser Doppler...

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Aim. To assess the influence of concomitant chronic obstructive pulmonary disease (COPD) on the parameters of left ventricular-arterial interaction in patients with ischemic cardiomyopathy (ICMP).Material and methods. We examined 130 patients with ICMP and 42 patients with ICMP and COPD. All patient...

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Objective: to study and compare the influence of such factors as: gender, age, family status, level of education and the frequency of determination of the international normalized ratio (INR) on the compliance of patients after mitral valve replacement (MC) with mechanical prostheses in dynamics - a...

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Aim. Create an algorithm predicting the risk of development of paroxysmal atrial fibrillation in patients with coronary heart disease on the background of post-infarction cardiosclerosis (PICS).Material and Methods. There was conducted the deep analysis of a number of laboratory and functional indic...

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The content of endothelium-1 and C-type natriuretic peptide in the blood plasma in correlation with the gene polymorphism of endothelial nitric oxide synthase was studied in 35 patients with chronic obstructive pulmonary disease (COPD), 35 patients with arterial hypertension (AH) and in 40 patients...

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We have studied the levels of markers of collagen exchange 280 in infertile and fertile patients with chronic prostatitis. All patients were divided into 2 groups: group 1 - sterile (140 persons) and group 2 - fertile patients matched for age (140 people). The mean age of patients was 34 [22; 43]. T...

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Aim. To study and analyze the levels of oxidative stress (OS) markers (malondialdehyde (MDA), superoxide dismutase (SOD), advanced oxidation protein products (AOPPs)) depending on the left ventricular ejection fraction (LVEF) and functional class (FC) in patients with chronic heart failure (CHF).Mat...

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Objective: to analyze the level of neopterin in patients with chronic heart failure (CHF) with a preserved fraction ejection fraction depending on the stage of the disease. Materials and methods: were examined 148 patients with CHF with preserved ejection fraction (50% and >) and 30 as a cont...

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A correlation analysis to identify the relationship between markers of endothelial dysfunction (coefficient of endothelial function - EFC, type C natriuretic peptide, endothelin-1) and indicators reflecting the activity of inflammation (C - reactive protein, fractalkine) in patients with chronic obs...

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In this research, the authors established the role of fractalkine as a marker of inflammatory activity at concomitant respiratory cardiac pathology, which flows with potentization of systemic inflammatory reactions. We found that in patients with arterial hypertension (AH), and in patients with chro...

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This study examines the characteristics ventricular-arterial interaction and the efficiency of left ventricle in patients with ischemic cardiomyopathy. We examined 120 male patients (mean age 57,4±1,9 years) with ischemic cardiomyopathy. The comparison group consisted of 80 patients matched for gend...

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Objective: To study the levels of heat shock protein 70 (HSP70) and annexin V-dependent apoptosis of cells in myocardial infarction (MI) with a different course of the disease and in the setting of chronic obstructive pulmonary disease (COPD).Materials and Methods: Sixty-five patients with MI were e...

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Background. Chronic obstructive pulmonary disease is a socially significant disease affecting patient’s quality of life. Assessment of endogenous intoxication in patients with chronic obstructive pulmonary disease will allow to understand pathogenetic features of different phenotypes of this disease...

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Objective: to estimate the incidence of recurrent myocardial infarction, stroke, and mortality in patients with different phenotypes of myocardial infarction against the background of chronic obstructive pulmonary disease.   Materials and methods: 325 patients with myocardial infarction were examine...

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Objective: To study and analyze serum levels of interleukins (IL): IL-1β, IL-2 and IL-6 in patients with myocardial infarction and chronic obstructive pulmonary disease.Materials and methods: In 85 people were examined: 28 patients with myocardial infarction, 37 patients with comorbid pathology (myo...

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Aim. To analyze the levels of fractalkine, neopterin and C-reactive protein (CRP) in patients with chronic heart failure (CHF) depending on the left ventricular ejection fraction (LVEF) and stage of the disease.Material and methods. We examined 340 people (280 patients with CHF) divided into groups...

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To estimate a functional condition of a myocardium of the left ventricle we examined 36 patients with the moderate course of bronchial asthma (BA), 39 patients with the heavy course of the disease and 30 somatic healthy patients. According to the results of echokardioskopic examination of the patien...

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