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  1. 1
    Evidence born from ASCOT trial – still important after 15 years

    Evidence born from ASCOT trial – still important after 15 years by O. P. Rotar

    Published 2021-09-01

    The paper presents the overview evolution of hypertension identification and treatment during last 15 years after publication of ASCOT trial (AngloScandinavian Cardiac Outcomes Trial) results. It discusses possible mechanism of more significant cardiovascular risk reduction in amlodipine/ perindopri...

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  2. 2
    Personalized approach to the treatment of patients with arterial hypertension: focus on imidazoline receptor agonists. Opinion on the problem

    Personalized approach to the treatment of patients with arterial hypertension: focus on imidazoline receptor agonists. Opinion on the problem by E. I. Baranova, V. Ionin, O. P. Rotar

    Published 2025-03-01

    Hypertension (HTN) remains one of the most pressing problems of modern healthcare. Morbidity and mortality associated with HTN continue to increase, despite a wide range of available antihypertensive agents and regular updates of related clinical guidelines. In October 2024, an annual forum was held...

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  3. 3
    The prevalence of electrocardiographic abnormalities in the Russian population in the early 21st century (the ESSE-RF study)

    The prevalence of electrocardiographic abnormalities in the Russian population in the early 21st century (the ESSE-RF study) by G. A. Muromtseva, V. G. Vilkov, V. V. Konstantinov, A. D. Deev, E. V. Oshchepkova, O. P. Rotar, S. A. Shalnova

    Published 2018-12-01

    Electrocardiography (ECG) takes the lead in assessing the prevalence of coronary artery disease (CAD) in the population. ECG disorders, grouped in the Major (certain) and Minor (possible) categories, are prognostic markers of a high risk of cardiovascular diseases and sudden cardiac death. Unified a...

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  4. 4
    HEALTH OF THE CARDIOLOGISTS: WHO IF NOT THEY?

    HEALTH OF THE CARDIOLOGISTS: WHO IF NOT THEY? by O. P. Rotar, A. V. Orlov, М. A. Boyarinova, V. N. Solntsev, A. A. Tanicheva, A. O. Konradi, E. V. Shlyakhto

    Published 2017-06-01

    Aim. To assess the prevalence of cardiovascular risk factors among clinicians attended the Russian National Congress of Cardiology (Ekaterinburg, September 20-23, 2016).Material and methods. During the Congress, 535 participants were screened on the presence of cardiovascular risk factors. Participa...

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  5. 5
    ASSOCIATION OF THE METABOLIC SYNDROME CONSTITUENTS WITH MARKERS OF SUBCLINICAL TARGET ORGAN DAMAGE DURING FOLLOW-UP OF INTELLECTUAL LABORERS

    ASSOCIATION OF THE METABOLIC SYNDROME CONSTITUENTS WITH MARKERS OF SUBCLINICAL TARGET ORGAN DAMAGE DURING FOLLOW-UP OF INTELLECTUAL LABORERS by O. P. Rotar, M. A. Boyarinova, E. V. Moguchaya, E. P. Kolesova, A. M. Erina, V. N. Solntsev, A. O. Konradi

    Published 2015-09-01

    Aim. To evaluate the relation of metabolic syndrome (MS) and its constituents with markers of subclinical damage of target organs (TOD) in follow-up of almost healthy intellectual laborers.Material and methods. From the selection of 1600 employees of a bank we randomly selected 383 with at least one...

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  6. 6
    DISTRIBUTION OF LIPID PROFILE VALUES IN ECONOMICALLY ACTIVE MEN AND WOMEN IN RUSSIAN FEDERATION: RESULTS OF THE ESSE-RF STUDY FOR THE YEARS 2012-2014

    DISTRIBUTION OF LIPID PROFILE VALUES IN ECONOMICALLY ACTIVE MEN AND WOMEN IN RUSSIAN FEDERATION: RESULTS OF THE ESSE-RF STUDY FOR THE YEARS 2012-2014 by A. N. Meshkov, A. I. Ershova, A. D. Deev, V. A. Metelskaya, Yu. V. Zhernakova, O. P. Rotar, S. A. Shalnova, S. A. Boytsov

    Published 2017-08-01

    Elevated level of plasma cholesterol, together with arterial hypertension, is the main modifiable factor of cardiovascular diseases (CVD) development. Monitoring of lipid levels at populational level is an important instrument of the prevention medicine, applied for CVD populational risk assessment....

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  7. 7
    ASSESSMENT OF HEALTHY LIFESTYLE COMPLIANCE AMONG PRIVATE-PRACTICE DOCTORS AND STUDENTS (MEDICAL STUDENTS, INTERNS AND CLINICAL RESIDENTS)

    ASSESSMENT OF HEALTHY LIFESTYLE COMPLIANCE AMONG PRIVATE-PRACTICE DOCTORS AND STUDENTS (MEDICAL STUDENTS, INTERNS AND CLINICAL RESIDENTS) by O. P. Rotar, A. V. Orlov, M. A. Boyarinova, V. N. Solntsev, A. A. Tanicheva, Yu. V. Sviryaev, A. O. Konradi, E. V. Shlyakhto

    Published 2018-12-01

    Introduction. The role of healthy lifestyles in the prevention of chronic non-communicable diseases is very important. Lifestyle of medical personnel, especially future doctors, may have great influence on healthy lifestyle compliance of patients. The objective of our study was to compare the preval...

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  8. 8
    Arterial stiffness and endothelial function in the long-term period after a coronavirus disease 2019

    Arterial stiffness and endothelial function in the long-term period after a coronavirus disease 2019 by S. A. Bondar, O. P. Rotar, E. V. Moguchaya, M. А. Boyarinova, E. P. Kolesova, E. Yu. Vasilyeva, A. A. Mikhailova, T. L. Karonova, A. O. Konradi

    Published 2024-06-01

    Aim. To assess endothelial function and arterial stiffness over time in patients after hospitalization with coronavirus disease 2019 (COVID-19) and compare them with a control group.Material and methods. A total of 53 patients over 18 years of age were hospitalized for COVID-19 in June — August 2021...

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  9. 9
    Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study. Ten years later

    Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study. Ten years later by S. A. Boytsov, O. M. Drapkina, E. V. Shlyakhto, A. O. Konradi, Yu. A. Balanova, Yu. V. Zhernakova, V. A. Metelskaya, E. V. Oshchepkova, O. P. Rotar, S. A. Shalnova

    Published 2021-09-01

    The growing weight of noncommunicable diseases, primarily cardiovascular diseases (CVDs), is a great threat to the health of population worldwide, worsening the quality of life and reducing life expectancy. Realization of this threat led to initiation of epidemiological study by the Russian Ministry...

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  10. 10
    ROLE OF THE NOTCH1 GENE IN FORMATION OF AORTIC ANEURYSM

    ROLE OF THE NOTCH1 GENE IN FORMATION OF AORTIC ANEURYSM by O. V. Irtyuga, O. A. Freilichman, D. S. Krivonosov, A. B. Malashicheva, S. I. Tarnovskaya, V. Е. Uspenskiy, M. L. Gordeev, O. P. Rotar, A. A. Kostareva, O. M. Moiseeva

    Published 2018-08-01

    Aim. To evaluate the impact of genetics in development of thoracic aneurysm in patients with tricuspid valve (TAV) and bicuspid aortic valve (BAV) based on the analysis and search for mutations in NOTCH1.Material and methods. In the study, 60 patients included with the dilation of thoracic aorta mor...

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  11. 11
    Hormonal determinants of prehypertension in a random sample of St. Petersburg residents: data from the ESSE-RF study

    Hormonal determinants of prehypertension in a random sample of St. Petersburg residents: data from the ESSE-RF study by A. M. Erina, M. A. Boyarinova, E. V. Moguchaya, E. P. Kolesova, E. Yu. Vasilyeva, A. S. Alieva, N. A. Paskar, O. P. Rotar, E. I. Baranova, A. O. Konradi, E. V. Shlyakhto

    Published 2021-06-01

    Aim. To determine the association of prehypertension (PHTN) with cardiometabolic and hormonal factors in a population sample of St. Petersburg residents.Material and methods. As part of the ESSE-RF epidemiological study, a random sample of 1600 residents of St. Petersburg at the age of 25-64 was exa...

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  12. 12
    ARTERIAL HYPERTENSION WORKGROUP RESOLUTION. THE ROLE OF SARTANS IN TREATMENT OF SYSTEMIC HYPERTENSION IN THE 21ST CENTURY

    ARTERIAL HYPERTENSION WORKGROUP RESOLUTION. THE ROLE OF SARTANS IN TREATMENT OF SYSTEMIC HYPERTENSION IN THE 21ST CENTURY by A. O. Konradi, O. N. Zhdanova, O. P. Rotar, Yu. A. Karpov, V. I. Podzolkov, P. A. Lebedev, A. I. Chesnikova, D. V. Nebieridze, O. N. Miller, E. V. Solovjova, A. N. Kulikov

    Published 2018-04-01

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  13. 13
    RELATIONSHIP OF SLEEP-DISORDERED BREATHING, EMOTIONAL COMPLAINTS AND ANTROPOMETRIC MEASUREMENTS (THE RESULTS OF SCREENING SURVEY AMONG SAINT-PETERSBURG CITIZENS)

    RELATIONSHIP OF SLEEP-DISORDERED BREATHING, EMOTIONAL COMPLAINTS AND ANTROPOMETRIC MEASUREMENTS (THE RESULTS OF SCREENING SURVEY AMONG SAINT-PETERSBURG CITIZENS) by E. A. Dubinina, S. L. Korostovtseva, O. P. Rotar, E. V. Moguchaya, M. A. Boyarinova, E. P. Kolesova, A. S. Alieva, S. O. Kravchenko, N. A. Paskar, Yu. V. Sviryaev, A. N. Alyokhin, A. O. Konradi

    Published 2014-11-01

    Aim. To assess the prevalence of sleep-disordered breathing (SDB), their relation to emotional complaints, antropometric measures and life-style factors in representative cohort of a large city inhabitants (Saint-Petersburg).Material and methods. Using structured interview and antropometric methods...

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  14. 14
    Favorable pattern of arterial stiffness and vascular aging in a unique cohort of offspring of early life famine survivors

    Favorable pattern of arterial stiffness and vascular aging in a unique cohort of offspring of early life famine survivors by K. M. Tolkunova, D. A. Usoltsev, E. V. Moguchaia, M. A. Boyarinova, A. M. Erina, E. P. Kolesova, S. V. Kibkalo, E. Yu. Vasileva, N. N. Artemov, O. P. Rotar, A. O. Konradi, E. V. Shlyakhto

    Published 2023-08-01

    The impact of adverse factors in the early life can affect the rate of vascular aging in adulthood and be passed on to the next generations.Aim. To study the characteristics of arterial stiffness and vascular aging phenotypes in two generations of descendants (children and grandchildren) of the sieg...

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  15. 15
    INFLAMMATORY MEDIATORS ROLE IN ATHEROSCLEROTIC LESION DEVELOPMENT IN THE LARGE ARTERIES IN PATIENTS WITH SYSTEMIC SCLERODERMIA

    INFLAMMATORY MEDIATORS ROLE IN ATHEROSCLEROTIC LESION DEVELOPMENT IN THE LARGE ARTERIES IN PATIENTS WITH SYSTEMIC SCLERODERMIA by A. L. Maslyansky, E. P. Kolesova, A. V. Kozlenok, E. Yu. Vasilieva, I. N. Penin, O. P. Rotar, N. M. Lazareva, S. V. Lapin, K. A. Sysoev, V. N. Solntsev, A. N. Bazhenov, A. O. Konradi

    Published 2015-06-01

    Aim. To evaluate the prevalence of atherosclerosis, to define the type of atherosclerotic lesion of brachiocephalic arteries in patients with systemic sclerodermia (SSD); to reveal the main factors influencing that process.Material and methods. Totally 38 patients with SSD studied. We measured vesse...

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  16. 16
    Basic Anthropometric Indices and Diabetes Mellitus Type 2 in Russian Population

    Basic Anthropometric Indices and Diabetes Mellitus Type 2 in Russian Population by O. M. Drapkina, R. N. Shepel, S. A. Shalnova, A. D. Deev, Yu. A. Balanova, S. E. Evstifeeva, Yu. V. Zhernakova, A. E. Imaeva, A. V. Kapustina, G. A. Muromtseva, O. P. Rotar, E. V. Shlyakhto, S. A. Boytsov

    Published 2018-11-01

    Obesity is one of the main risk factors for type 2 diabetes developing. The question of the advantages and disadvantages of using various anthropometric indices [body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHR), lipid accumulation product index (LAPI), visceral obesity in...

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  17. 17
    EMOTIONAL STATUS AND FOOD PREFERENCE STYLE: THE RESULTS OF THE EPIDEMIOLOGICAL STUDY ESSE-RF IN SAINT-PETERSBURG, SAMARA AND ORENBURG

    EMOTIONAL STATUS AND FOOD PREFERENCE STYLE: THE RESULTS OF THE EPIDEMIOLOGICAL STUDY ESSE-RF IN SAINT-PETERSBURG, SAMARA AND ORENBURG by O. P. Rotar, Е. А. Dubinina, A. V. Orlov, R. A. Libis, E. N. Isaeva, I. R. Basyrova, D. V. Duplyakov, S. A. Gudkova, V. N. Solntsev, A. N. Alyokhin, E. I. Baranova, A. O. Konradi, E. V. Shlyakhto

    Published 2015-08-01

    Aim. To study the relation of emotional status with negative tendencies in food preference style in Russian population, including regional specifics of Saint-Petersburg, Samara and Orenburg. Material and methods. The study is the part of ESSE-RF (Epidemiology of Cardiovascular diseases in different...

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  18. 18
    Vascular aging phenotypes in Russian population — biological, social, and behavioral determinants

    Vascular aging phenotypes in Russian population — biological, social, and behavioral determinants by O. P. Rotar, M. A. Boiarinova, K. M. Tolkunova, E. V. Moguchaia, A. S. Alievа, A. V. Orlov, E. P. Kolesova, A. M. Erina, D. A. Usoltsev, V. N. Solntsev, E. I. Baranova, A. O. Konradi, E. V. Shlyakhto

    Published 2021-09-01

    Aim. To assess the association of cardiovascular risk factors with various vascular aging phenotypes using the St. Petersburg population sample as part of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study.Material and methods. The cur...

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  19. 19
    Appointment of lipid-lowering therapy in the Russian population: comparison of SCORE and SCORE2 (according to the ESSE-RF study)

    Appointment of lipid-lowering therapy in the Russian population: comparison of SCORE and SCORE2 (according to the ESSE-RF study) by A. M. Erina, D. A. Usoltsev, M. A. Boyarinova, E. P. Kolesova, E. V. Moguchaya, K. M. Tolkunova, A. S. Alieva, O. P. Rotar, N. N. Artemov, S. A. Shalnova, A. O. Konradi, O. M. Drapkina, S. A. Boytsov, E. V. Shlyakhto

    Published 2022-06-01

    Aim. In 2021, the European Society of Cardiology (ESC) guidelines for the prevention of cardiovascular diseases (CVDs) were published, where a new SCORE2 CVD risk assessment model was introduced. In our work, we compared approaches to determine the indications for initiating lipid-lowering therapy i...

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  20. 20
    METABOLIC SYNDROME PREVALENCE IN RUSSIAN CITIES

    METABOLIC SYNDROME PREVALENCE IN RUSSIAN CITIES by O. P. Rotar, R. A. Libis, E. N. Isaeva, A. M. Erina, D. A. Shavshin, E. V. Moguchaya, E. P. Kolesova, M. A. Boyarinova, N. V. Moroshkina, O. I. Yakovleva, V. N. Solntsev, A. O. Konradi, E. V. Shlyakhto

    Published 2012-04-01

    Aim. Metabolic syndrome (MS) is a combination of the key cardiovascular risk factors, namely obesity, carbohydrate metabolism disturbances, arterial hypertension (AH), and dyslipidemia. MS prevalence varies, depending on the MS definition used. The aim of this study was to assess the prevalence of M...

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