Search Results - O. L. Barbarash

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Biomarkers are often used as a surrogate measure in the assessment of risk, severity, and prognosis of the disease. For the optimal use of biomarkers in predicting cardiovascular risk, they should demonstrate reproducibility in sequential quantitative measurements and show high sensitivity and speci...

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Myocardial infarction is a formidable manifestation of coronary artery disease and accounts for one third of deaths associated with coronary disease. In Russia, from 400 to 500 thousand patients with acute coronary syndrome are hospitalized annually, about half of them with myocardial infarction (MI...

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The review contains actual data on possible approaches aimed at improving the prognosis in a special category of patients with extremely high cardiovascular risk, as well as in patients with recent acute coronary syndrome combined with comorbidity, including multifocal atherosclerosis. Currently, th...

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Currently, there is no information in novel clinical guidelines on the importance of active detection of atrial fibrillation (AF) in myocardial infarction (MI), as well as on the management of such patients. The aim of this review was to present actual information about possible risk factors, featur...

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Here we provide a brief overview of current consensus documents and clinical guidelines concerning the management of the patients with acute coronary syndrome (ACS) without ST segment elevation, which have been released in 2021-2022. Further, we consider statistics on ACS in the Russian Federation a...

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Aim. To assess the relationship between frailty syndrome (FS) and physical activity (PA) in patients with multivessel coronary artery disease (CAD).Material and methods. The study included 387 patients with CAD. To identify prefrailty and FS, the authors used the questionnaire “Age is not a drawback...

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Aim. The evaluation of the prominence of subclinical nonspecific inflammation in men and women with ST-elevation myocardial infarction (STEMI) with different one year outcomes.Material and methods. Totally 223 patients with STEMI included — 56 (25,1%) women, 167 (74,9%) men. At 10-14 day of hospital...

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The review article presents current data on the clinical and prognostic significance, as well as on the prevalence of comorbidities in patients with atrial fibrillation (AF). The prevalence of hypertension, diabetes and heart failure in patients with AF is discussed according to the Russian and fore...

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The review is devoted to the analysis of literature data on the features of the course, diagnosis and treatment of myocardial infarction at a young age. Despite the relevance of the problem of myocardial infarction in young people, there is no specific approach to the management and examination of s...

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The review article provides with recent data on the crucial cardiology problems — duration of double antiplatelet therapy (DAPT) in patients with different types of ischemic heart disease. The analysis is provided of actual clinical guidelines on this issue, the results of recent clinical trials are...

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Aim. To study the effect of azilsartan medoxomil (AZL-M) on the 24-hour blood pressure (BP) profile in patients with hypertension (HTN), type 2 diabetes (T2D) and stable coronary artery disease (CAD).Material and methods.  A total of 183 patients with CAD in combination with HTN and T2D took part in...

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The review article presents the state-of-the-art of use of dual antiplatelet therapy (DAPT) in patients with acute coronary syndrome (ACS) based on modern clinical guidelines and in actual clinical practice. The main differences in the frequency of use and duration of DAPT in different countries are...

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Dietary modifications are an effective method for the prevention and treatment of cardiovascular diseases and their risk factors: hypertension, hyperglycemia, obesity, dyslipidemia. Large-scale studies have shown the causal relationship between eating behavior (predominant consumption of fruits, veg...

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Aim. To evaluate efficacy, safety and influence on quality of life of controlled release metoprolol tartrate (CRMT) in patients with arterial hypertension of 1-3 degree.Material and methods. 603 patients (256 men and 347 women; 60,1 y.o., in average) with hypertension of 1-3 degree were examined. 67...

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Psychosocial factors determining prognosis in patients with acute myocardial infarction.

Aim. To evaluate neurodynamics parameters in young and middle-aged patients with arterial hypertension (AH).Material and methods. In total, 41 men with AH (main group), aged 38-59 years, were examined. The control group included 15 healthy men (mean age 42,4+1,5 years). Interviewing, physical examin...

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Invasive management of patients with ST- segment elevation acute coronary syndrome (ST-ACS) and non-ST-elevation acute coronary syndrome (NSTE-ACS) is a priority and reflected in the current guidelines for management of this category of patients with a high evidence level (class I, level of evidence...

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Aim. To assess the role of matrix metalloproteinases (MMPs) in pathological remodeling of the left ventricular myocardium in patients with ST-segment elevation myocardial infarction (STEMI).Materials and Methods. We recruited 175 consecutive patients with STEMI (average age 61.3 (range 47-89) years,...

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