検索結果 - Ning Liu

Junctional adhesion molecule-like protein (JAML), a member of the junctional adhesion molecule (JAM) family, is widely expressed in various cells. This review examines the progress made in understanding JAML, beginning with its discovery and subsequent characterization. It emphasizes the mechanisms...

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Ubiquitin-specific protease 7 (USP7), a deubiquitinase enzyme responsible for removing ubiquitin (Ub) from target proteins, plays a crucial role in oncogenic pathways and has been implicated in various human diseases. X-ray crystallography has revealed distinct conformations of USP7, including apo (...

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This paper investigates the framework of wireless rechargeable sensor network (WRSN) assisted by multiple mobile unmanned vehicles (MUVs) and laser-charged unmanned aerial vehicles (UAVs). On the basis of framework, we cooperatively investigate the trajectory optimization of multi-UAVs and multi-MUV...

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Purpose The incidence of alcoholic liver cirrhosis (ALC) has been gradually rising in recent years, with a poor prognosis. This study aimed to investigate the association between the red blood cell distribution width–platelet ratio (RPR) and the in-hospital mortality risk among patients with ALC.Met...

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Slurry-cast (SLC) electrode manufacturing faces problems such as thickness limitation and material stratification, which are caused by applying toxic organic solvents. Solvent-free electrode technology, as a sustainable alternative, could get rid of issues generated by solvents. In this study, dual-...

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The Colorado potato beetle (CPB), Leptinotarsa decemlineata Say, is an infamous invasive species worldwide. It was first found in Xinjiang Uygur Autonomous Region of China in 1993 and spread to Northeast China in 2013. To better understand the genetic structure and the diffusion path of their popula...

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Firebreaks and fuel treatments are critical means for the reduction of wildfire threat and damage to human infrastructure in forest landscapes. However, the uncertain behavior of wildfires makes the planning of firebreaks challenging, especially when available resources are insufficient to treat all...

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The normal modes cannot be extracted even in the Pekeris waveguide when the source-receiver distance is very close. This paper introduces a normal mode extraction method based on a dedispersion transform (DDT) to solve this problem. The method presented here takes advantage of DDT, which is based on...

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Summary: Neuromuscular diseases such as amyotrophic lateral sclerosis and sarcopenia cause muscle atrophy, which preferentially affects fast-twitch glycolytic myofibers. The mechanisms underlying the susceptibility of fast myofibers to disease remain unclear. To investigate this, we analyzed the tra...

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With the rapid development of renewable energy, the co-combustion of Zhundong coal and biomass has attracted more and more attention. However, the high content of alkali metals in Zhundong coal and biomass leads to serious slagging and fouling in the co-combustion process. In this study, cotton stra...

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In complex environments such as high dynamics and weak signals, a satellite signal compensation method based on prefabricated trajectory assistance and an improved adaptive Kalman filter is proposed for a 155 mm differential rotating rear-body control-guided projectile to address the situation of sa...

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Abstract Background Temozolomide (TMZ), which is an alkylating agent, is the standard chemotherapeutic drug used for glioma treatment. However, the development of resistance to TMZ limits its efficacy. Thus, identifying novel therapeutic targets is necessary. Methods In this study, the levels of mid...

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Petrocodon parviflorus, a new species of Gesneriaceae, is a typically cave-dwelling species from the limestone region in Guangxi, China. Morphologically, this new species resembles P. lui, but can be readily distinguished by differences in corolla limb lobe shape, calyx lobe surface texture, pistil...

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Proper application of nitrogen (N) fertilizers and irrigation management are important production practices that can reduce nitrate leaching into groundwater and improve the N use efficiency (NUE). A lysimeter/rain shelter facility was used to study effects of the rate of N fertilization, type of N...

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Laccases, as a kind of multicopper oxidase, play an important role in pigment synthesis and growth in fungi and are involved in their interactions with host plants. In Setosphaeria turcica, 9 laccase-like multicopper oxidases have been identified, and StLAC2 is involved in the synthesis of the melan...

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<i>Bombyx mori</i>, a key lepidopteran model with economic importance, is highly susceptible to environmental heavy metal pollution. This study investigated the mechanisms of Pb toxicity and the associated detoxification and metabolic defense responses in silkworms, employing transcripto...

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Lodging stress results in grain yield and quality reduction in wheat. Uniconazole, a potential plant growth regulator significantly enhances lignin biosynthesis and thus provides mechanical strength to plants in order to cope with lodging stress. A field study was conducted during the 2015–2016 and...

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Summary: Dabieshan tick virus (DBTV), a tick-borne virus belonging to the genus Uukuvirus in the family Phenuiviridae, exhibits potential pathogenicity to humans and animals. However, its geographic distribution and transmission dynamics remain poorly understood. In this study, we analyzed 1,352 tic...

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Hydraulic legged robots, with advantages such as high load capacity and power density, have become a strategic driving force in advancing intelligent mobile platform technologies. However, their high energy consumption significantly limits long-duration endurance and efficient operational performanc...

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