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    TunR2, a novel mode-of-action tunicamycin-type antibiotic: Pharmacokinetics in C57BL/6 mouse and Holstein cattle

    TunR2, a novel mode-of-action tunicamycin-type antibiotic: Pharmacokinetics in C57BL/6 mouse and Holstein cattle by Maria A. Colombatti Olivieri, Eric D. Cassmann, Michael A. Jackson, Neil P. J. Price, John P. Bannantine

    Published 2025-01-01 Get full text
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    TunR2, a novel mode-of-action tunicamycin-type antibiotic: Pharmacokinetics in C57BL/6 mouse and Holstein cattle.

    TunR2, a novel mode-of-action tunicamycin-type antibiotic: Pharmacokinetics in C57BL/6 mouse and Holstein cattle. by Maria A Colombatti Olivieri, Eric D Cassmann, Michael A Jackson, Neil P J Price, John P Bannantine

    Published 2025-01-01

    We have investigated the pharmacokinetics of TunR2, a modified tunicamycin-type antibiotic, in mice and cattle. TunR2 has previously been shown to be effective in a mycobacterial disease model using zebrafish, with a minimal activation of the eukaryotic unfolded protein response (upr) and a reductio...

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