Search Results - Nan Chen

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  1. 1

    Evolutionary Game of Medical Knowledge Sharing Among Chinese Hospitals Under Government Regulation by Liqin Zhang, Na Lv, Nan Chen

    Published 2025-06-01

    This study investigates the evolutionary game dynamics of medical knowledge sharing (KS) among Chinese hospitals under government regulation, focusing on the strategic interactions between general hospitals, community health service centers, and governmental bodies. Leveraging evolutionary game theo...

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  2. 2

    Does the reduction in obstetric hospitals result in an unintended decreased in-hospital delivery utilisation? A causal multilevel analysis in China by Jay Pan, Nan Chen, Peter C Coyte

    Published 2025-06-01

    Introduction China’s progress towards achieving Sustainable Development Goals for maternal health is largely attributed to a reduction in maternal mortality rates, driven by increased in-hospital delivery services utilisation. However, recent reductions in the number of obstetric hospitals have rais...

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  3. 3

    Psychiatric safety associated with hormone replacement therapy for menopausal symptoms: a real-world study of the FDA adverse event reporting system by Nan Chen, Lei Li, Chun-li Fu, Yi Ren

    Published 2025-06-01

    BackgroundMenopause is a significant phase in a woman’s life and is characterized by the cessation of ovarian function and a decline in endogenous ovarian hormone levels. This hormonal transition is often accompanied by debilitating symptoms, such as hot flushes, which can significantly impair quali...

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  4. 4

    Nonuniformity Correction for Variable-Integration-Time Infrared Camera by Nan Chen, Jiqing Zhang, Shengyou Zhong, Zhongshun Ji, Libin Yao

    Published 2018-01-01

    A two-dimensional calibration technique is proposed to correct the spatial nonuniformity in infrared imaging systems adapting to different integration time and time-varying offset with one-time calibration. Differing from traditional calibration-based nonuniformity correction, this method calibrates...

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  5. 5

    Shanling Jiangzhi Tea treats hyperuricemia by inhibition of COMT/MAOA signaling pathway and p53/SERPINE1/NLRP3 signaling pathway by Hao-nan Chen, Hao-nan Chen, He-zhen Wu, He-zhen Wu, He-zhen Wu, Yan-fang Yang, Yan-fang Yang, Yan-fang Yang

    Published 2025-07-01

    ObjectiveTo evaluate the therapeutic efficacy of Shanling Jiangzhi Tea (SLJZ) on hyperuricemia (HUA) mice and to investigate its mechanism.MethodsA HUA mouse model was established using a combination of uric acid (UA)and potassium oxonate. Following SLJZ intervention, changes in body weight were mon...

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  6. 6

    Establishment of age-stratified serum vitamin B6 pyridoxal and pyridoxic acid reference intervals among children aged 1–16 years in Henan, china by Yusheng Luan, Nan Chen, Xucheng Wang, Xiaojuan Li, Junmei Yang, Tiewei Li

    Published 2025-07-01

    Background/ObjectiveThe development of population-specific reference intervals (RIs) for serum vitamin B6 (B6) in Chinese pediatric populations has not been established. Current clinical practice relies on international thresholds, but diagnostic sensitivity with domestic biochemical profiles remain...

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  7. 7

    A Compact and Broadband Photonic Crystal Fiber Polarization Filter Based on a Plasmonic Resonant Thin Gold Film by Min Chang, Baixuan Li, Nan Chen, Xinglian Lu, Xuedian Zhang, Jian Xu

    Published 2019-01-01

    A novel high birefringence gold-coated photonic crystal fiber (PCF) polarization filter based on surface plasmon resonance is proposed. The six elliptical holes arranged in a specific mode surrounding the core are utilized to gain high birefringence, and gold is coated inside the air holes to genera...

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  8. 8

    Hybrid preprocessing and ensemble classification for enhanced detection of Parkinson's disease using multiple speech signal databases by Ling-Chun Sun, Chun-Wei Tseng, Ke-Feng Lin, Ping-Nan Chen

    Published 2025-06-01

    Objective With the increasing prevalence of Parkinson's disease (PD) and the development of PD-based acoustic recording databases, this study aims to evaluate the feasibility of using an ensemble-based machine learning (ML) approach to detect PD across diverse acoustic datasets. Methods We util...

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  9. 9

    Design of a Metal-Filled Photonic-Crystal Fiber Polarization Filter Based on Surface Plasmon Resonance at 1.31 and 1.55&#x00A0;<inline-formula><tex-math notation="LaTeX">$\mu$</tex... by Xinglian Lu, Min Chang, Nan Chen, Xuedian Zhang, Songlin Zhuang, Jian Xu

    Published 2018-01-01

    A metal-filled photonic crystal fiber (PCF) polarization filter based on surface plasmon resonance (SPR) is proposed and designed. The structure of the cross-section of a PCF is composed of a hexagonal lattice of air holes, in which an air hole is selectively filled with metal. We realize the polari...

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  10. 10

    Robotic radical hysterectomy is superior to laparoscopic radical hysterectomy and open radical hysterectomy in the treatment of cervical cancer. by Yue-Mei Jin, Shan-Shan Liu, Jun Chen, Yan-Nan Chen, Chen-Chen Ren

    Published 2018-01-01

    <h4>Objective</h4>Cervical cancer (CC) continues to be a global burden for women, with higher incidence and mortality rates reported annually. Many countries have witnessed a dramatic reduction in the prevalence of CC due to widely accessed robotic radical hysterectomy (RRH). This networ...

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  11. 11

    Positive Selection Drives Mitochondrial Gene Rearrangement in Sternorrhyncha (Insecta: Hemiptera) by Tian‐You Zhao, Jiu‐Feng Wei, Cai‐Feng Li, Ya‐Nan Chen, Liang Lü, Fang Wang

    Published 2025-07-01

    ABSTRACT Sternorrhyncha, a suborder of Hemiptera, comprises sap‐feeding insects with piercing‐sucking mouthparts, most of which are important agricultural and forestry pests, including aphids, psyllids, whiteflies, and scale insects. While the mitochondrial genome is a highly accessible molecular so...

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  12. 12

    MF‐UFNO: A Fourier Neural Operators‐Based Model for Radar Echo Extrapolation by Tingting Ye, Weihua Ai, Dachao Jin, Zhonghui Tan, Li Wang, Fenghua Ling, Xi Liu, Nan Chen, Senshen Hu

    Published 2025-07-01

    Abstract Severe convective weather events, such as heavy rainfall and flooding, are serious threats to human society. However, accurate nowcasting of these events using radar remains challenging due to the complex dynamics and nonlinear physical processes involved. Moreover, existing radar echo extr...

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  13. 13

    Design, synthesis and evaluation of antifungal activity of 8-hydroxyquinolin-5-ylidene thiosemicarbazone derivatives by Haonan Zhang, Xiaochen Chi, Zhe Ji, Jiayin Wang, Futang Liu, Nan Chen, Qingli Guo, Yuanying Jiang, Tingjunhong Ni

    Published 2025-01-01

    Over the past decades, the incidence and modality of invasive fungal infections have been significantly underestimated. And the limited availability of clinically effective antifungals further underscores the need for novel therapeutic agents. In this study, a series of novel 8-hydroxyquinolin-5-yli...

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  14. 14

    Prognostic value of tissue inhibitor of metalloproteinase-2 expression in patients with non-small cell lung cancer: a systematic review and meta-analysis. by Lin Zhu, Hong Yu, Shi-Yuan Liu, Xiang-Sheng Xiao, Wei-Hua Dong, Yi-Nan Chen, Wei Xu, Tong Zhu

    Published 2015-01-01

    <h4>Background and objectives</h4>Tissue inhibitor of metalloproteinase-2 (TIMP-2) is a small secretory glycoprotein with anti-matrix metalloproteinase activity. Data on the value of TIMP-2 as a prognostic factor in non-small cell lung cancer (NSCLC) are discordant and remain controversi...

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  15. 15

    Cascaded Brillouin, Raman, and Four-Wave-Mixing Generation in a 1.06-&#x03BC;m Microsphere-Feedback Yb-Fiber Laser by Shuisen Jiang, Changlei Guo, Zhengqian Luo, Deyu Tang, Chenshuang Xiao, Changyan Ren, Kaijun Che, Nan Chen, Huiying Xu, Zhiping Cai

    Published 2018-01-01

    We propose and experimentally demonstrate a compact microresonator-feedback single-frequency fiber laser at 1.06&#x00A0;&#x03BC;m, and further initiating different-type nonlinear lasing based on stimulated Brilliouin scattering, stimulated Raman scattering, and four-wave mixing (FWM). A sili...

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  16. 16

    Low Resistivity and High Carrier Concentration in SnO<sub>2</sub> Thin Films: The Impact of Nitrogen–Hydrogen Annealing Treatments by Qi-Zhen Chen, Zhi-Xuan Zhang, Wan-Qiang Fu, Jing-Ru Duan, Yu-Xin Yang, Chao-Nan Chen, Shui-Yang Lien

    Published 2025-06-01

    The tin dioxide (SnO<sub>2</sub>) thin films in this work were prepared by using plasma-enhanced atomic layer deposition (PEALD), and a systematic analysis was conducted to evaluate the influence of post-deposition annealing at various temperatures in a nitrogen–hydrogen mixed atmosphere...

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  17. 17

    Research on the construction of corneal endothelium transplantation with acellular amniotic membrane as a scaffold by Ya-Nan Chen, Rui-Qin Guo, Bo-Yu Liang, Hong-Qin Ke, Meng-Jie Dong, Ming-Fang He, Ji Yang, Hai Liu

    Published 2025-07-01

    IntroductionThis study aimed to develop a human acellular amniotic membrane (HAAM) scaffold suitable for corneal endothelial transplantation. The HAAM was engineered using sequential chemical treatments and physical agitation to remove cellular components while preserving the extracellular matrix st...

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  18. 18

    Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways by Shi-Long Wang, Si Liang, Si Liang, Si-Yu Li, Jin-Wen Fu, Zi-Yi-Ru Wang, Dong-Qing Zhu, Nan Chen

    Published 2025-07-01

    IntroductionNon-alcoholic fatty liver disease (MASLD) is a common liver condition with a global prevalence of approximately 25%, often associated with overweight, obesity, and abnormalities in glucose and lipid metabolism. Its histological hallmark is hepatic steatosis. Non-alcoholic steatohepatitis...

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  19. 19

    Screening of host proteins interacting with the African swine fever virus outer membrane protein CD2v by Xiong-nan Chen, Xiong-nan Chen, Xiong-nan Chen, Gao-xi Zhu, Gao-xi Zhu, Gao-xi Zhu, Yi-xian Li, Yi-han Hao, Yi-han Hao, Yi-han Hao, Yi-fan Liang, Yi-fan Liang, Chen Hu, Ying-shuo Sun, Ying-shuo Sun, Yun-zhao Peng, Yun-zhao Peng, Xi Li, Xi Li, Xi Li, Zhao Huang, Zhao Huang, Zhao Huang, Gui-hong Zhang, Gui-hong Zhang, Gui-hong Zhang, Lang Gong, Lang Gong, Lang Gong, Ze-zhong Zheng, Ze-zhong Zheng, Ze-zhong Zheng, Ze-zhong Zheng

    Published 2025-06-01

    BackgroundThe African swine fever virus (ASFV) is a highly pathogenic double-stranded DNA virus that poses a significant threat to the global swine industry. Although the CD2v protein encoded by ASFV is a key factor in viral immune evasion and pathogenicity, the mechanism underlying its interaction...

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  20. 20

    Lower respiratory tract microbiome dysbiosis impairs clinical responses to immune checkpoint blockade in advanced non‐small‐cell lung cancer by Yong Zhang, Xiang‐Xiang Chen, Ruo Chen, Ling Li, Qing Ju, Dan Qiu, Yuan Wang, Peng‐Yu Jing, Ning Chang, Min Wang, Jian Zhang, Zhi‐Nan Chen, Ke Wang

    Published 2025-01-01

    Abstract Background Gut microbiome on predicting clinical responses to immune checkpoint inhibitors (ICIs) has been discussed in detail for decades, while microecological features of the lower respiratory tract within advanced non‐small‐cell lung cancer (NSCLC) are still relatively vague. Methods Du...

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