Search Results - N. V. Kolesnikova
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CLINICAL AND IMMUNOLOGICAL EFFICACY OF MURAMYLDIPEPTIDE (GMDP) IN FERTILITY DISORDERS (scientific review)
Published 2017-11-01Get full textAim. The analysis of literature data on the peculiarities of immunity in physiological pregnancy and its complications, as well as the possibility of correction of fertility disorders using muramyldipeptide.Recent deterioration of reproductive health is largely due to socio-economic stresses and unf...
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COMPARATIVE ANALYSIS IMMUNOTROPIC EFFECTS IN VITRO DERINAT AND SYNTHETIC TLR9 AGONIST ON RECEPTOR FUNCTION OF NEUTROPHILIC GRANULOCYTES AND MONOCYTES IN NORMAL AND INFECTIOUS PROCE...
Published 2016-10-01Get full textComparative evaluation of character of the expression of TLR9 and CD11b receptors by neutrophilic granulocytes and monocytes whole blood under the influence of Derinat and synthetic TLR9 ligand in healthy individuals and in acute infectious diseases of viral and bacterial origin has been studied. It...
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PRO – AND ANTI-INFLAMMATORY CYTOKINES ARE EARLY MARKERS OF ACUTE REJECTION OF THE TRANSPLANTED KIDNEY
Published 2018-07-01Get full textAim. Determination of diagnostic significance of pro − and anti-inflammatory cytokines in early prognosis of posttransplant renal failure in patients with chronic renal disease.Materials and methods. In the peripheral blood of patients with chronic kidney disease 6 hours before kidney transplantatio...
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Local cytokine status with laboratory animals in various periods after intraocular shape memory implant administration in experimental ophthalmology
Published 2016-02-01Get full textExperimental estimation of pro- and anti-inflammatory cytokines balance in aqueous eye chamber liquid in case of intraocular implantation of drainage material made of nickelid titanium and intraocular application of a solid retention suture TH-10. Investigation of aqueous eye chamber liquid sampled...
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Monitoring of cytokine level moisture in aqueous chamber during surgical debridement of observational penetrating wounds of eye cornea with nickelid titanium suture material
Published 2014-08-01Get full textComparative assessment of cytokine profile status in aqueous chamber moisture with experimental rabbits while use of traditional suture material and nickelid titanium monolithic fibers with penetrating wounds of eye cornea has been done. It has been approved within the course of examinations (3, 7,...
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Modern Approaches to the Treatment of Patients with External Genital Endometriosis, Conjugated with Sterility
Published 2011-06-01Get full textPurpose: To prove pathogenically the addition of immunocorrection in a complex treatment of an external endometriosis conjugated with the sterility, and to access its effectiveness.Materials and Methods: There are two groups of patients: the I group (73 patients) – received Roncoleikin in a complex...
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CLINICAL AND IMMUNOLOGICAL CHANGES IN TREATMENT OF ADENOMYOSIS IN PATIENTS WITH INFERTILITY
Published 2017-11-01Get full textAim. The aim of this study was to asses changes of adhesion molecules (L-selectin, neopterin and interleukin-6) in patients with adenomyosis-related infertility during the therapy.Materials and methods. 49 patients with infertility caused by adenomyosis were examined and divided into 3 clinical grou...
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CLINICAL AND IMMUNOLOGICAL EFFICIENCY OF MURAMYL DIPEPTIDE IN THE TREATMENT OF ATOPIC DISEASES
Published 2016-04-01Get full textIncreased incidence of allergic diseases worldwide reflects some mangles of the existing pharmacotherapy concept which ignores some etiopathogenetic aspects of clinical atopy. Meanwhile, understanding cellular and molecular mechanisms of allergy may create prerequisites for development of new therap...
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Clinical and immunological aspects of early reproductive losses in patients with adenomyosis
Published 2020-04-01Get full textAim. To evaluate the clinical and immunological features of the early gestational period in patients with adenomyosis.Materials and methods. The study included 110 patients with first spontaneous pregnancy in 6–9 weeks. 75 pregnant women with a history of grade 1 adenomyosis were divided into two gr...
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CHEMOKINE MARKERS ASSOCIATED WITH EARLY REJECTION OF KIDNEY ALLOGRAFT
Published 2019-10-01Get full textIt is known at the present time that immunological biomarkers may become more sensitive, non-invasive methods of graft rejection diagnosis than those currently used. A growing amount of studies in animal models shows that chemokines, as active participants in the immune process, may be used to this...
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Level of local cytokine production in the event of nickelid titanium suture material use in experimental surgical hypotension eye operation
Published 2016-06-01Get full textComparative assessment of cytokine moisture in aqueous chamber with experimental rabbits while use of nickelid titanium suture and in case of traditional suture material in hypotension operations. During the experiment, moisture in aqueous chamber has been studied with 10 adult rabbits, the samples...
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FEATURES OF THE IMMUNE STATUS OF WOMEN OF REPRODUCTIVE AGE SUFFERING FROM GENITAL INFECTIOUS-INFLAMMATORY PROCESSES
Published 2017-12-01Get full textAim. A comprehensive assessment of the various links of immunity in women of reproductive age with genital infectious-inflammatory processes. Materials and methods. The study used peripheral blood of 30 patients with inflammatory diseases of the pelvic organs (IDPO), 30 patients with a viral infecti...
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LEVEL OF LOCAL PRODUCTION OF CYTOKINES IN THE CLINIC OF TRADITIONAL TREATMENT OF DEMODECTIC BLEPHARITIS AND IN CONDITIONS OF LID CRYOTHERAPY USE
Published 2017-12-01Get full textAim. A comparative cytokine profile assessment of the lacrimal fluid of the eyes of patients in the clinic of traditional treatment of demodectic blepharitis, and using the course of cryotherapy of the eyelids by an autonomous cryoapplicator made of titanium nickelide. Materials and methods. Clinica...
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