Search Results - N. V. Furman

Interval QT prolongation is a predictor of the life-threatening cardiac arrhythmias — polymorphic ventricular tachycardia (torsade de pointes). Long QT syndrome may be congenital or acquired. It is known that a wide range of both antiarrhythmic and non-cardiac medications might lead to QT interval p...

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Aim. То investigate the link between dynamics of QT and QTa duration and dispersion, corrected QT and QTa (QTc, QTac) in coronary heart disease (CHD) patients undergoing treadmill stress test, with ventricular arrhythmia registration. Material and metliods. In total, 77 patients with Functional Clas...

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Aim. To study a potential link between increased QT dispersion (dQT) during physical stress test (PST) and coronary artery (CA) atherosclerosis in patients with coronary heart disease (CHD).Material and methods. In total, 116 CHD patients with Functional Class II-III angina were examined (mean age 4...

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Myocardial bridging (MB) is congenital abnormality of the coronary arteries, which typically does not interfere with long term prognosis, but in some cases can cause myocardial infarction and other life-threatening conditions. This article reviews current knowledge about the anatomy, pathophysiology...

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Aim. To evaluate the pre-hospital treatment of patients with acute coronary syndromes (acute myocardial infarction and unstable angina) in 2001 and 2006.Material and methods. Retrospective pre-hospital treatment survey was performed in 1114 patients with acute coronary syndrome (acute myocardial inf...

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Aim. To evaluate the structure of drug prescriptions in acute coronary syndrome (acute myocardial infarction and unstable angina) on the first day of hospital therapy in Saratov city and Saratov region.Material and methods. Retrospective pharmacoepidemiology study was carried out in 1276 patients wi...

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Aim. To analyze pharmacotherapy of cerebral infarction in patients with atrial fibrillation (AF) in real clinical practice of neurological departments of Saratov hospitals.Material and methods. A retrospective longitudinal pharmacoepidemiologic study was carried out. Medical cards were analyzed in p...

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Aim. To estimate the prevalence of atherothrombotic complications depending on platelet sensitivity to acetylsalicylic acids (ASA) in patients with stable angina.Material and methods. 96 patients with stable angina of II-III functional classes received basic therapy included ASA (125 mg daily) to pr...

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Atherothrombosis is a complication of ischemic heart disease, and it leads to development of acute coronary syndrome. Atherothrombosis is characterized by sudden destruction of atherosclerotic plaque, which results into platelets activation and thrombus formation. Aspirin - one of the most widely us...

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Aim. To analyze current clinical practice in the treatment of atrial fibrillation (AF) in emergency care department of multidisciplinary hospital in 2008-2009. Material and methods. Retrospective continuous pharmacoepidemiology study was carried out. Hospital history sheets of the patients admitted...

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Inhibitors of the renin-angiotensin-aldosterone system, statins, and possibly , ω-3 polyunsaturated fatty acids may influence the incidence of atrial fibrillation (AF), and can be used to prevent it. In recent medical literature, this approach is referred to as upstream treatment. The results of exp...

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Aim. To compare direct medical costs of dabigatran and warfarin therapy in patients with non-valvular atrial fibrillation (NVAF) during preparation for elective cardioversion. Material and methods. An open non-randomized study was conducted to evaluate direct medical costs (cost of drug, cost of the...

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Aim. To evaluate risk of repeated atherothrombotic events in patients survived acute coronary syndrome (ACS) and having poorly reduced platelet aggregation (proven by optical aggregometry) in response to acetylsalicylic acid (ASA) therapy.Material and methods. 200 patients with ACS (aged 56,6±9,2 y....

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Monitoring of the effectiveness of drug therapy is one of the most debated issues in everyday clinical practice. The emergence of new drugs,  methods of analysis, standards, management protocols, and clinical guidelines increases the information load on practitioners and requires a significant inves...

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Aim. To study the prevalence of high residual platelet reactivity (HRPR) during the dual antiplatelet therapy (DAT) with acetylsalicylic acid (ASA) and clopidogrel by optical aggregometry in patients with ischemic heart disease (IHD) after percutaneous transluminal coronary angioplasty (PTCA) in cli...

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Aim. To compare features of pharmacotherapy of patients with chronic heart failure (CHF) with a reduced ejection fraction of the left ventricle (LV EF) who were admitted in a specialized department of the multidisciplinary hospital in Saratov before and after the publication of the Russian National...

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Estimation of cardiovascular risk is discussed. Serum lipoproteins, glucose, fibrinogen, von Willebrand factor, tissue-type plasminogen activator, C-reactive protein etc are offered for use as laboratory indicators. At the same time new markers of high cardiovascular risk are under development. D-di...

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Aim. To study the changes that have occurred in the pharmacotherapy of atrial fibrillation (AF) in the Saratov Region for 5 years by analyzing the antithrombotic therapy of patients who were admitted in a specialized department of the multidisciplinary hospital in Saratov in 2011-2012 and in 2016-20...

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Aim. To analyze gender differences in pharmacotherapy and outcomes of ST-elevation myocardial infarction (STEMI) in patients of cardiology hospital in real clinical practice. Material and methods. A continuous pharmacoepidemiological analysis was performed on the base of 153 records of patients with...

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