Search Results - N. V. Balatskaya

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  1. 1
    COVID-19 and problems of ophthalmology

    COVID-19 and problems of ophthalmology by V. V. Neroev, G. I. Krichevskaya, N. V. Balatskaya

    Published 2020-12-01

    Coronaviruses (CoV) are a large group of RNA viruses that are pathogenic to animals and humans. Until the end of the 20th century, human CoV were known as pathogens of seasonal mild respiratory diseases. In the last 20 years new CoVs caused three outbreaks of severe acute respiratory diseases with a...

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  2. 2
    Mechanisms of immune regulation and transplantation immunity in corneal transplants

    Mechanisms of immune regulation and transplantation immunity in corneal transplants by V. V. Neroev, N. V. Balatskaya, E. V. Chentsova, Kh. M. Shamkhalova

    Published 2020-01-01

    At the present time, corneal transplantation (keratoplasty) is one of the most frequent modes of solid tissue transplants in the world. Unlike other kinds of transplants, corneal grafting is often performed without tissue typing and systemic immunosuppression.High frequency of transparent corneal en...

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  3. 3
    Immune privilege in the subretinal space and prospects of retinal pigment epithelium transplantation in degenerative diseases of the retina

    Immune privilege in the subretinal space and prospects of retinal pigment epithelium transplantation in degenerative diseases of the retina by N. V. Neroeva, N. V. Balatskaya, L. A. Katargina, A. G. Brilliantova

    Published 2023-12-01

    Damage of the retinal pigment epithelium (RPE) underlies the pathogenesis of degenerative-dystrophic diseases of the retina, in particular, age-related macular degeneration (AMD) — one of the leading causes of irreversible loss of central vision, blindness and elderly population disability. Advanced...

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  4. 4
    Significance of assessing the inflammatory markers of vascular wall activation in age-related macular degeneration

    Significance of assessing the inflammatory markers of vascular wall activation in age-related macular degeneration by N. V. Balatskaya, E. P. Vorobyova, I. G. Kulikova, A. E. Andryushin

    Published 2025-07-01

    Among the numerous pathogenetic factors of age-related macular degeneration (AMD), special attention has been recently paid to endothelial dysfunction (ED), since the vascular endothelium is an important internal component of the the hematoretinal barrier (IBRB) providing immunological homeostasis o...

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  5. 5
    Proinflammatory chemokines in the development of systemic organ-specific sensitization in infectious corneal ulcers

    Proinflammatory chemokines in the development of systemic organ-specific sensitization in infectious corneal ulcers by N. V. Balatskaya, I. G. Kulikova, L. A. Kovaleva, P. V. Makarov

    Published 2020-05-01

    Purpose. The aim is to estimate the content of proinflammatory chemokines (CXCL1/GRO-α CXCL8/IL-8, CXCL10/IP-10, CXCL12/ SDF-1α, CCL2/MCP-1, CCL3/MIP-1α, CCL4/MIP-1β, CCL5/RANTES, CCL11/Eotaxin) in blood serum in corneal ulcers and their relationship to the cellular immune response to corneal and uv...

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  6. 6
    Facilities of diagnosis and monitoring of optic neuropathy in primary open-angle glaucoma. Part 1

    Facilities of diagnosis and monitoring of optic neuropathy in primary open-angle glaucoma. Part 1 by O. A. Kiseleva, N. V. Balatskaya, A. M. Bessmertny, V. I. Kotelin

    Published 2019-06-01

    The review is focused on modern methods of instrumental diagnostics of primary open-angle glaucoma. Diagnostic possibilities and informativeness of objective measurable parameters are discussed with regard to special criteria, called clinical endpoints.

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  7. 7
    Local and systemic production of 45 cytokines in complicated proliferative diabetic retinopaty

    Local and systemic production of 45 cytokines in complicated proliferative diabetic retinopaty by V. V. Neroev, O. V. Zaytseva, N. V. Balatskaya, A. A. Lazutova

    Published 2020-04-01

    Diabetic retinopathy (DR) is multifactorial by its origin, involving many cytokines and growth factors. Studies of cytokine levels in biological fluids seem to be relevant for an in-depth understanding of the disease pathogenesis. The purpose of the work was a comparative analysis of 45 cytokines at...

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  8. 8
    LOCAL AND SYSTEMIC VEGF-А PRODUCTION IN COMPLICATED PROLIFERATIVE DIABETIC RETINOPATHY

    LOCAL AND SYSTEMIC VEGF-А PRODUCTION IN COMPLICATED PROLIFERATIVE DIABETIC RETINOPATHY by V. V. Neroev, O. V. Zaytseva, N. V. Balatskaya, Z. V. Kurchaeva

    Published 2016-08-01

    VEGF-A contents was studied in blood serum, lacrimal fluid, and vitreous body of patients with different clinical forms of complicated proliferative diabetic retinopathy (PDR). The study included 50 patients with diabetes mellitus (type I, II), twelve patients with rhegmatogenous retinal detachment...

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  9. 9
    FREQUENCY OF DEVIATIONS FROM NORMAL VALUES IN THE BLOOD SUBPOPULATIONS’ PROFILE IN THE PATIENTS WITH CENTRAL CORNEAL ULCERS

    FREQUENCY OF DEVIATIONS FROM NORMAL VALUES IN THE BLOOD SUBPOPULATIONS’ PROFILE IN THE PATIENTS WITH CENTRAL CORNEAL ULCERS by I. G. Kulikova, N. V. Balatskaya, L. A. Kovaleva, P. V. Makarov

    Published 2018-03-01

    This article presents a detailed description of shifts in subsets of blood lymphocyte subpopulations associated with development of the corneal ulcerative lesions as well as during penetrating keratoplasty.We have revealed some general changes typical for patients with corneal ulcer and patients wit...

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  10. 10
    The significance of reactivation of latent herpes simplex viruses type 1 and 2 in the etiopathogenesis of chronic inflammatory eye diseases and the development of late post-uveal complications

    The significance of reactivation of latent herpes simplex viruses type 1 and 2 in the etiopathogenesis of chronic inflammatory eye diseases and the development of late post-uveal c... by G. I. Krichevskaya, E. S. Sorozhkina, N. V. Balatskaya, L. A. Kovaleva, G. A. Davydova

    Published 2024-12-01

    Herpes simplex viruses type 1 and 2 (HSV-1 and HSV-2) cause widespread lifelong infections. These characteristics of herpes simplex virus infections (HSVI) are associated with the presence of two phases in the infectious cycle: the lytic infection phase, which involves the formation of new viral par...

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  11. 11
    Predictive model of small choroidal melanoma progression after eye-saving treatment based on clinical, morphometric and immunological parameters

    Predictive model of small choroidal melanoma progression after eye-saving treatment based on clinical, morphometric and immunological parameters by E. B. Myakoshina, I. G. Kulikova, N. V. Balatskaya, L. A. Katargina, S. V. Saakyan

    Published 2022-03-01

    Choroidal melanoma is a malignant tumor characterized by early metastasis and poor vital prognosis. Prognostic indexes for the tumor development are of importance, depending on various factors and making it possible to optimize therapeutic measures. Usage of present models for prediction of the uvea...

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  12. 12
    Clinical Aspects of Bacterial Corneal Ulcer Prolonged Course, the Role of Herpes Viruses in Its Pathogenesis, Treatment

    Clinical Aspects of Bacterial Corneal Ulcer Prolonged Course, the Role of Herpes Viruses in Its Pathogenesis, Treatment by V. V. Neroev, L. A. Katargina, L. A. Kovaleva, G. I. Krichevskaya, N. V. Balatskaya

    Published 2019-04-01

    Purpose: to study the role of human herpesviruses (HHV) in the pathogenesis of prolonged bacterial corneal ulcers. Patients and methods. 117 patients with bacterial corneal ulcer were examined. Two groups were identified: a favorable course-with duration of bacterial corneal ulcer epithelialization...

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  13. 13
    Characterization of Shifts of the Cellular Component the Immune Status of Patients with Long-Term Course of Chronic Post-Traumatic Uveitis

    Characterization of Shifts of the Cellular Component the Immune Status of Patients with Long-Term Course of Chronic Post-Traumatic Uveitis by N. V. Balatskaya, I. A. Filatova, I. G. Kulikova, V. O. Denisyuk, I. M. Mohammad

    Published 2021-04-01

    Purpose: to study the subpopulation composition of peripheral blood lymphocytes in patients with long — term chronic post-traumatic uveitis (CPT).Patients and Methods. There were 131 people aged 17 to 87 years, who received the surgical treatment in the Department of plastic surgery and eye prosthet...

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  14. 14
    Clinical significance of assessing the subpopulation composition of blood lymphocytes in patients with infectious corneal lesions in high-risk keratoplasty

    Clinical significance of assessing the subpopulation composition of blood lymphocytes in patients with infectious corneal lesions in high-risk keratoplasty by V. V. Neroev, N. V. Balatskaya, E. V. Chentsova, I. G. Kulikova, H. M. Shamkhalova

    Published 2020-09-01

    The purpose is to study the shifts in the subpopulation composition of blood lymphocytes in patients with infectious corneal lesions, depending on the number of keratoplasties (KP) undergone by the patient.Material and methods. We examined 53 patients (aged 18 to 79) with infectious keratitis, divid...

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  15. 15
    Facilities of diagnosis and monitoring of optic neuropathy in primary open-angle glaucoma. Part 2

    Facilities of diagnosis and monitoring of optic neuropathy in primary open-angle glaucoma. Part 2 by O. A. Kiseleva, N. V. Balatskaya, A. M. Bessmertny, L. V. Yakubova, V. I. Kotelin

    Published 2020-03-01

    The first part of the review was focused on modern methods of instrumental diagnostics of primary open-angle glaucoma [1]. Diagnostic possibilities and informativeness of objective measurable parameters were discussed with regard to special criteria, called clinical endpoints. The second part of the...

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  16. 16
    Proven and less studied hematopoietic and vasoactive growth factors in retinal capillary hemangioma

    Proven and less studied hematopoietic and vasoactive growth factors in retinal capillary hemangioma by V. V. Neroev, N. V. Balatskaya, A. Yu. Novikova, M. V. Ryabina, P. A. Ilyukhin

    Published 2020-12-01

    Pathogenesis of retinal capillary hemangioma has not been sufficiently studied at the present time. Therefore, the study of cytokine levels in biological fluids seems to be very relevant in order to increase knowledge about the mechanisms of the disease development and searching for targeted therapi...

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  17. 17
    PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION

    PERIPHERAL BLOOD SUBPOPULATION OF LYMPHOCYTES OF PATIENTS WITH AGE-RELATED MACULAR DEGENERATION by N. V. Balatskaya, E. A. Eremeeva, O. S. Slepova, M. V. Ryabina, I. G. Kulikova, E. S. Sorozhkina

    Published 2015-10-01

    The article presents results of studies concerning subрopulations of peripheral blood lymphocyte in the patients at early stages of age-related macular degeneration (AMD), being compared with healthy elderly persons (risk group for AMD), and young adults without ophthalmological problems. We have re...

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  18. 18
    Clinical features of Behcet’s uveitis in patients with herpesvirus reactivation

    Clinical features of Behcet’s uveitis in patients with herpesvirus reactivation by V. V. Neroev, E. S. Sorozhkina, G. I. Krichevskaya, N. V. Balatskaya, G. A. Davydova, T. A. Lisitsyna

    Published 2022-12-01

    Purpose. To study the possible impact of human herpes viruses (HHV) reactivation: herpes simplex virus type 1 (HSV 1), type 2 (HSV 2), cytomegalovirus (CMV) and Epstein — Barr virus (EBV) on the clinical course of uveitis in Behcet's disease (BD). Material and methods. Serum samples of 106 BD p...

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  19. 19
    Experimental assessment of the impact of high acoustic power ultrasound diagnostics on animal eyes

    Experimental assessment of the impact of high acoustic power ultrasound diagnostics on animal eyes by M. S. Zaitsev, T. N. Kiseleva, K. V. Lugovkina, N. V. Balatskaya, E. V. Jani, K. E. Seliverstova

    Published 2022-09-01

    Purpose: to study the impact of diagnostic ultrasound of high acoustic power on animal eye tissues in the experiment.Material and methods. 46 Chinchilla rabbits (92 eyes) were divided into the main group of 38 rabbits (76 eyes) and the control group of 8 rabbits (16 intact eyes). Animals of the main...

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  20. 20
    Features of the Composition of Cytokines of Various Biological Effects in Patients with Uveal Melanoma: Local Changes in the Lacrimal Fluid. Part 1

    Features of the Composition of Cytokines of Various Biological Effects in Patients with Uveal Melanoma: Local Changes in the Lacrimal Fluid. Part 1 by V. V. Neroev, S. V. Saakyan, L. A. Katargina, N. V. Balatskaya, I. G. Kulikova, E. B. Myakoshina

    Published 2022-04-01

    Purpose. Conduct an extended analysis of the cytokine status and its role in inflammatory processes in uveal melanoma based on multiplex analysis of the tear fluid.Patients and methods. Immunological studies of blood serum and lacrimal fluid were performed in 80 patients with uveal melanoma and 38 h...

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