Search Results - N N Kuzmina

Objective: to estimate a need for conservative rehabilitation treatment in patients with juvenile chronic arthritis (JCA).Material and methods. Data on the principles and procedures of rehabilitation treatment were analyzed in patients with JCA on the basis of 25- year experience. The need for these...

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Basing on the data of home and foreign literature and on the long-term experience of pediatric rheumatologists, terminologic and classification aspects of Juvenile rheumatoid arthritis (JRA) are presented. Approaches to developing of diagnostic and classification of JRA criteria in future are descri...

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PFAPA (periodic fever, aphtous stomatitis, pharingitis, cervical adenitis) or Marshall’s syndrome is one of the rare periodic fever conditions appearing in children. Its cause is unknown. This syndrome may continue for several years. During interictal period the child is quite well, grows and develo...

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Objective. 7 cases of AHA syndrome (arthralgia, arthritis, hives, angioneuroticedema) in children described. Literature and own data are presented. Possible pathogenetic mechanisms, clinical symptoms and treatment are discussed.

Хронические артриты у детей являются важной проблемой современной педиатрии в силу того, что эти тяжелые заболевания существенно нарушают качество жизни ребенка и его родителей, требуют немалых экономических затрат на лечение и нередко приводят к инвалидности ребёнка. Этиология этих заболеваний в на...

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The paper gives the experience of the V.A. Nasonova Research Institute of Rheumatology in identifying and managing patients with familial Mediterranean fever (FMF). Objective: to describe the features of the disease in patients with FMF in Russia and to compare them with the data obtained in the stu...

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The article presents the development of the doctrine of autoinflammatory diseases (AID) in the last decade. Data on interleukin 1, inflammasomes and their role in the development of AID are presented. The paper also contains the data about interferonopathies and, in particular, proteasomal illnesses...

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Cryopyrin-associated periodic syndromes (CAPS) are the most prominent representatives of monogenic autoinflammatory diseases (AIDs). They are characterized by a concurrence of fever, rash, and other symptoms that are accompanied by disabling or life-threatening complications. Based on the current gu...

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The paper presents the main milestones of a long-term study of the time course of acute rheumatic fever (ARF) in a Russian contingent of patients from different age groups, the results of studying of the clinical types of the disease, developing, and introducing methods for its diagnosis, treatment,...

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The paper deals with the most common classical autoinflammatory disease familial Mediterra-nean fever (FMF)/periodic disease. This is a monogenic hereditary disease caused by mutations with an autosomal recessive pattern of inheritance. The most common types of mutations are given. Hyperactivation o...

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The program for the prevention of acute rheumatic fever (ARF) and recurrent attacks of the disease includes primary and secondary prevention. The basis for the primary prevention of ARF are activities aimed at increasing the level of the body’s innate immunity and adaptive responses to adverse envir...

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Despite considerable advances in the control of acute rheumatic fever (ARF), the problem of this disease remains relevant and contains a number of unsolved issues as before. The paper displays an epidemiological update on ARF and analyzes a number of provisions of the recent (2015) American Heart As...

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In pediatrics, rheumatic diseases (RD) are characterized by particularly severe social consequences. This investigation was undertaken to clarify the prevalence of RD from the 2009—2010 statistical data of the Ministry of Health and Social Development of the Russian Federation. Analysis of these dat...

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Aim: To present modern approaches to the systemic therapy by glucocorticosteroids (GCS) basing on own experience and literature data. Methods and material: Long-term observation of 350 patients with juvenile rheumatoid arthritis (JRA) taking peroral GCS in different dosage. Results: Good therapeutic...

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The paper presents the clinical characteristics of Behcet's disease (BD) in Russian children, generally accepted criteria for BD, and diagnosis statement. The investigation is based on an observation of 17 children who met the international criteria for BD and were treated at the V.A. Nasonova...

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168 patients aged 4-15 years were endoscopically examined aiming at the study of prevalence and structure of NSAID - gustropathy in children with rheumatic diseases. Serious injury of mucous of upper gastrointestinal tract (erosions and ulcers) were found in 21% of children with prevalent localizati...

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