Search Results - Mingrui Liu
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The application of high-degree freedom titanium alloy implant based on TPMS in the repair of metacarpal bone defects
Published 2025-08-01Get full textHigh design freedom is crucial for enhancing personalized manufacturing. Although extensive research has explored the relationship between lattice design, mechanical properties, and bone integration in 3D-printed implants, limited literature exists on their design and application in personalized imp...
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Validation of Experimental Cooling Performance of Multi-Stage Thin-Film Thermoelectric Devices via Numerical Simulation
Published 2025-05-01Get full textIn-plane thermoelectric thin-film cooling devices are considered a promising solution for thermal management in electronic systems. However, the actual cooling performance is far below that of regular bulk cooling devices, making the design of thin-film devices much more difficult. In this work, a n...
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Melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1
Published 2025-07-01Get full textA major obstacle in type 2 diabetes mellitus (T2DM) is sleep fragmentation (SF), which negatively affects testicular function. However, the underlying mechanisms remain to be elucidated. In this study, we demonstrate that SF induces testicular damage through a mechanism involving lipid metabolism, s...
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Neuraminidase 1 Exacerbated Glycolytic Dysregulation and Cardiotoxicity by Destabilizing SIRT1 through Interactions with NRF2 and HIF1α
Published 2025-07-01Get full textAbstract Despite significant therapeutic advances, cumulative DOX‐induced cardiotoxicity (DIC) events remain unacceptably high. Recent evidence has underscored the critical role of impaired glycolytic metabolism in cardiovascular damage. Neuraminidase 1 (NEU1), a member of the neuraminidase family,...
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