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    USP10 protects against pressure overload-induced mitochondrial morphofunctional defects and pathological cardiac hypertrophy through stabilizing cytoplasmic Mfn2

    USP10 protects against pressure overload-induced mitochondrial morphofunctional defects and pathological cardiac hypertrophy through stabilizing cytoplasmic Mfn2 by Runjing Li, Feng Gao, Yunan Chen, Jiamin Zhao, Rui Shi, Man Li, Zhenzi Zuo, Pan Chang, Dema De, Lin Chen, Feng Fu, Mingge Ding

    Published 2025-09-01

    Increasing evidence has implicated the important role of mitochondrial morphofunctional defects in pathological myocardial hypertrophy and heart failure. Deubiquitinating enzymes (DUBs) are involved in protein stability maintenance and regulate multiple cellular processes, while it remains largely u...

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