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    METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

    METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response de réir Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu

    Foilsithe / Cruthaithe 2025-07-01

    Hepatocellular carcinoma (HCC) is among the most common causes of cancer‐related deaths worldwide. Previous studies showed that N6‐methyladenosine (m6A), the most abundant chemical modification in eukaryotic RNAs, is implicated in HCC progression. Using liver‐specific conditional knockout mice, we f...

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