Search Results - Mi-Ri Gwon
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Impact of Heavy Metals on the Antioxidant Activity of Vitamin D: A Metabolic Perspective
Published 2025-07-01Get full text<b>Background/Objectives</b>: Vitamin D (VD) is metabolized in the body and plays a crucial role in regulating the antioxidant system. While exposure to heavy metals (HMs) inhibits VD activity, HMs can also be absorbed following VD stimulation. Despite differing views on the interaction...
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Clinical Laboratory Parameter–Driven Machine Learning for Participant Selection in Bioequivalence Studies Among Patients With Gastric Cancer: Framework Development and Validation S...
Published 2025-05-01Get full textAbstract BackgroundInsufficient participant enrollment is a major factor responsible for clinical trial failure. ObjectiveWe formulated a machine learning (ML)–based framework using clinical laboratory parameters to identify participants eligible for enrollment in...
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LC-MS-Based Untargeted Metabolic Profiling in Plasma Following Dapagliflozin Administration in Healthy Volunteers
Published 2025-07-01Get full textDapagliflozin, a sodium-glucose cotransporter 2 inhibitor, treats type 2 diabetes by blocking renal glucose reabsorption and promoting urinary glucose excretion. This mechanism lowers blood glucose concentrations independently of insulin. The resulting caloric loss also contributes to weight reducti...
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