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    Animal model-based adjunctive herbal therapy in autism spectrum disorder: Therapeutic advances and prospects door Mohamed Lamine Toumi, Sameha Merzoug, Ghada Senane

    Gepubliceerd in 2025-03-01

    Autism spectrum disorder is a complex neurodevelopmental condition that poses major challenges to caregivers in contemporary societies. Since there is no established cure for this disorder so far, autistic patients of all ages are currently taken in charge of psychological and educational therapies...

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    Taxonomic Diversity and Antimicrobial Potential of Thermophilic Bacteria from Two Extreme Algerian Hot Springs door Marwa Aireche, Mohamed Merzoug, Amaria Ilhem Hammadi, Zohra Yasmine Zater, Keltoum Bendida, Chaimaa Naila Brakna, Meryem Berrazeg, Ahmed Yassine Aireche, Yasmine Saidi, Svetoslav Dimitrov Todorov, Dallel Arabet, Djamal Saidi

    Gepubliceerd in 2025-06-01

    This study investigated thermophilic bacterial communities from two Algerian hot springs: Hammam Debagh (94–98 °C), recognized as the second hottest spring in the world, and Hammam Bouhadjar (61–72 °C), one of the hottest in northwest Algeria. Thirty isolates were obtained, able to grow between 45 °...

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    Wnt/PKC Signaling Inhibits Sensory Hair Cell Formation in the Developing Mammalian Cochlea door Joanna F. Mulvaney, Erynn M. Layman, Farhana Feroze-Merzoug, Julia M. Abitbol, Jennifer M. Jones, Dara O’Connor, Florence Naillat, Seppo Vainio, Jeffrey S. Rubin, Matthew W. Kelley, Alain Dabdoub

    Gepubliceerd in 2025-06-01

    The establishment of cell fate and boundaries between cell types is an essential step in development and organogenesis. In the mammalian cochlea, a distinct boundary exists between a medial region of non-sensory cells and a lateral region of sensory cells. We report that Wnt4 and sFRP2 act in combin...

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