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    Impact of posttransplant cyclophosphamide-based GVHD prophylaxis in patients 70 years and older: an update from BMT CTN 1703

    Impact of posttransplant cyclophosphamide-based GVHD prophylaxis in patients 70 years and older: an update from BMT CTN 1703 由 Sameem Abedin, Michael J. Martens, Javier Bolaños-Meade, Monzr M. Al Malki, Qinghua Lian, Lyndsey Runaas, Hany Elmariah, Mahasweta Gooptu, Karilyn T. Larkin, Brian C. Shaffer, Alison W. Loren, Melhem Solh, Amin M. Alousi, Omer H. Jamy, Miguel-Angel Perales, Andrew Rezvani, Ami Bhatt, Najla El Jurdi, Janny M. Yao, Kristy Applegate, Leslie S. Kean, Yvonne A. Efebera, Ran Reshef, William Clark, Eric Leifer, Wael Saber, Mary M. Horowitz, Richard J. Jones, Shernan G. Holtan, Mehdi Hamadani

    出版 2025-07-01

    Abstract: Allogeneic hematopoietic cell transplant (allo-HCT) is underutilized in adults aged ≥70 years. Morbidity, often driven by graft-versus-host disease (GVHD), is considered a major barrier to its use. The BMT CTN 1703 trial (ClinicalTrials.gov identifier: NCT03959241) randomly assigned adults...

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