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    Pharmacodynamics, pharmacokinetics, interactions with other drugs, toxicity and clinical effectiveness of proton pump inhibitors

    Pharmacodynamics, pharmacokinetics, interactions with other drugs, toxicity and clinical effectiveness of proton pump inhibitors by Łukasz Wołowiec, Joanna Osiak-Gwiazdowska, Albert Jaśniak, Michał Janiak, Lidia Wydeheft, Magdalena Łukasiak, Małgorzata Pellowska, Grzegorz Grześk

    Published 2025-07-01

    The document comprehensively reviews proton pump inhibitors (PPIs), focusing on their pharmacodynamics, pharmacokinetics, drug interactions, toxicity, and clinical efficacy. PPIs irreversibly inhibit the H+/K+-ATPase enzyme in gastric parietal cells, effectively reducing gastric acid secretion. Thes...

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