Search Results - M. V. Mayevskaya

The aim of review. To present the definition of probiotics, to indicate principle of their action and international requirements to probiotic products, to review clinical studies of probiotic application in gastroenterology.Original positions. Original studies assume a set of positive properties of...

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Aim of investigation. To estimate efficacy and safety of «Phosphogliv» in combined therapy of patients with chronic hepatitis C (CHC), that received no previous antiviral treatment.Preliminary results. Four-week application of phosphogliv (glycirrhizinic acid) in a dose of 2,5 g iv 5 times per week,...

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The aim of review. To present modern data on the mechanism of action and clinical utilization of immunomodulating agent «Timosin alpha-1».Original positions of the report. Timosin alpha1 is 28-base acetylated polypeptide, that effectively modulates human immune system and has direct action on the ce...

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The aim of review. To present recent literature data on features of course of hepatitis B during pregnancy and major risk factors of infection of children via vertical route.Original positions. Course of chronic hepatitis B during pregnancy was studied in several cohort studies which demonstrated ,...

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The aim of review. To analyze problem of alcohol abuse and dangerous consequences related to it in Russian population, to demonstrate possible ways of its decision.The basic contents. According to official statistics, alcohol is one of leading factors of mortality in Russian population, making 11,9%...

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The aim of review. To discuss relation of obesity to phenomena of insulin resistance and lipotoxicity, and to demonstrate main therapeutic directions of their correction.Original positions. The most serious metabolic disorders related to obesity, include non-alcoholic fatty liver disease (NAFLD), di...

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Aim. This review study is aimed at characterizing the nutrition of patients with non-alcoholic fatty liver disease (NAFLD).General findings. A high-calorie diet, followed even for a short period of time, can lead to an increase in the lipid content in hepatocytes and an increase in ALT values. These...

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Aim of the clinical case presentation. To discuss the principles of the correct and healthy nutrition, which are the universal and applicable for the most of overweight and obese patients and obesity-related disorders, exemplified by clinical case. Summary. Obesity has multifactorial adverse effect...

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Aim of review. To consider different treatment options for dyslipidemia in non-alcoholic fatty liver disease (NAFLD). Summary. NAFLD occurs in 20-30% of adult population. In the Russian Federation its rate is estimated as high as 37,1%. In the most of NAFLD cases severe disorder of lipid metabolism...

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The aim of review. To discuss features of course of chronic hepatitis C virus infection at elderly, efficacy and safety of antiviral treatment of patients of this age group.Original positions. In every day clinical practice elderly patients with chronic hepatitis C are extremely rarely considered as...

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The aim of review. To discover the role of cytokines in pathogenesis of severe alcohol-induced hepatitis and to show directions for therapeutic action.Original positions. Cytokines is aggregative term including various groups of biologically active substances: interleukins, tumor necrosis factor-α f...

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The aim of review. To present main pathogenic aspects of development of alcohol-induced liver disease (ALD), principles of diagnostics and treatment of this disease.Original positions. The alcohol-induced liver disease includes some variants of parenchymal damage caused by regular alcohol intake: st...

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The aim of review. To present up-to-date references, that allows to choose the optimal mode of antiviral therapy for patient with chronic hepatitis B (CHB).Original positions. Chronic HBV-infection represents a major epidemiologic and economic problem all over the world. Liver cirrhosis (LC) and hep...

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The aim of review. To cite the literature data, confirming efficacy of ursodeoxycholic acid (UDCA) at alcoholic and non-alcoholic steatohepatitis (NASH).Original positions. Prevalence of liver steatosis as pathomorphologic substrate of various liver diseases is quite high, however the special attent...

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The aim of review. To analyze antiviral activity of a new NS5A replication complex inhibitor daclatasvir in patients with chronic HCV-infection in relation to different genotypes, including patients with failure of previous antiviral therapy, with liver cirrhosis, within different modes of treatment...

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The aim of review. To discuss potentials of application of new NS3/NS4 protease inhibitor faldaprevir at chronic hepatitis C with genotype 1 HCV, including patients without response to previous antiviral therapy, liver cirrhosis, and to estimate its antiviral activity in the range of treatment modes...

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The aim of review. To carry over for consideration the basic mechanisms of bacterial infections at liver cirrhosis (LC), their consequences, methods of diagnostics and prophylaxis.Original positions. Bacterial infections is a cause of high mortality in liver cirrhosis patients. These patients are mo...

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Aim of investigation. To determine the effect of bacterial overgrowth syndrome and translocation of bacterial DNA in ascitic fluid on morbidity in liver cirrhosis (LC) and long-term life expectancy.Material and methods. Overall 42 LC patients were included to original study (Child-Pugh class A – 15...

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Aim of investigation. To study prevalence of diffuse liver diseases in the Russian Federation by the example of large industrial city with application of screening tests. Material and methods. Overall 5000 Moscow inhabitants age 18 to 75 years, chosen randomly within the «the liver check up» project...

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The aim of review. Primary biliary cirrhosis (PBC) is related to the group of autoimmune cholestasisassociated liver diseases. In the last years prevalence of PBC increased considerably, especially – in Northern European countries. Despite of sufficient progress in studying of main pathophysiologica...

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