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A Novel Hybrid Methodology for Loss of Containment Accident Risk Assessment of Chemical Storage Tank Based on RPN Considering the Expert Epistemic Uncertainty
Published 2025-06-01Get full textIn the petrochemical industry, storage tank failures may lead to unfavorable consequences or even catastrophic events. The risk management of chemical tank farms must identify all possible failure modes and reduce the risk for critical failure modes. However, identifying and assessing failure modes...
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The facts about the effects of pedagogical agents on learners’ cognitive load: a meta-analysis based on 24 studies
Published 2025-07-01Get full textThe role of pedagogical agents in multimedia learning as an element that gives students social cues to promote cognition has been demonstrated in terms of enhancing students’ academic performance and intrinsic motivation. Cognitive load is an important factor in measuring the effectiveness of multim...
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Detection of seven phytohormones in peanut tissues by ultra-high-performance liquid chromatography-triple quadrupole tandem mass spectrometry
Published 2020-03-01Get full textDevelopment of highly sensitive and reliable method for detection of phytohormones is of great significance to study plant hormones and agricultural production. In this study, an ultra-high-performance liquid chromatography-mass spectrometry/mass spectrometry method was established for separation an...
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A Novel Intronic Mutation in MBD5 Results in Autosomal Dominant Intellectual Disability Type 1 due to Abnormal Splicing
Published 2025-07-01Get full textABSTRACT Background We identified a novel variant in MBD5 located within intron 6: c.114‐13A>G (NM_018328.5) in a family with a patient presenting intellectual disability. This variant is hypothesized to be the etiological agent underlying the patient's condition. Methods We conducted an ana...
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EV-A71 invades the central nervous system and affects the blood-brain barrier in a tree shrew model
Published 2025-06-01Get full textIntroductionThe enterovirus A71 (EV-A71)-caused central nerve system (CNS) damage seriously endangers the health of infants and young children, but the underlying mechanisms by which EV-A71 crosses the blood-brain barrier (BBB) are still largely unknown. This study developed a tree shrew (Tupaia bel...
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