Resultados de búsqueda - Lixin Wang

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  1. 1

    Discrete Element Method-Based Stratified Soil Modeling to Improve the Precision of Soil–Machine Interaction Simulations por Baoer Hao, Xuejie Ma, Lixin Wang, Xin Tong

    Publicado 2025-06-01

    This study presents an efficient method to determine discrete element model parameters at multiple soil depths and enhance the precision of soil–implement interaction simulations in agricultural machinery by integrating the JKR and Bonding contact models. The soil was divided into three layers based...

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  2. 2

    The Biomass Carbon Sequestration Potential in China's Drylands por Zimin Tan, Shuai Wang, Fangli Wei, Changjia Li, Fengyu Fu, Lixin Wang

    Publicado 2025-06-01

    Abstract Drylands are important carbon pools for climate change mitigation but remain highly vulnerable to climate and anthropogenic pressures. Despite China hosting one of the largest dryland areas globally, limited studies have quantified its biomass carbon storage and sequestration potential. Her...

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  3. 3

    miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling por Juanjuan Zhang, Lixin Wang, Yingye Shen, Xiaoli Qian, Zhiming Wang, Chenyang Wang

    Publicado 2025-07-01

    BackgroundMacrophage polarization represents a promising therapeutic target for inflammatory bowel disease (IBD). This study investigates the role of miRNA-223 (miR-223) in dextran sodium sulfate (DSS)-induced colitis and its regulation of macrophage polarization.MethodsMale C57BL/6 mice were assign...

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  4. 4

    Oppositely charged proteins lead to different effects on the bioaccumulation kinetics of polystyrene nanoplastics in zebrafish (Danio rerio) por Guoliang Zhang, Bowen Xiao, Tao Jiang, Tong Zhao, Jinhui Sun, Huamin Liu, Lixin Wang

    Publicado 2025-09-01

    Nanoplastics (NPs) are ubiquitous in the natural aquatic environment, thus there is a major need to understand their potential health risk toward aquatic organisms. Proteins are widely spread in the water environment, they may interact with NPs and significantly impact the ecotoxicology of NPs in vi...

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  5. 5

    Three-Dimensional-Printed Meat Products with Lycopene-Functionalized Yeast Pickering Emulsions as Fat Replacer por Zihan Cao, Yu Xing, Shasha Zhou, Feifan Li, Lixin Wang, Juanjuan Zhang, Xiaoxi Yang, Yumiao Lang

    Publicado 2025-07-01

    Due to the health-driven demand for fat replacers in meat products, Lycopene (Lyc)-loaded yeast protein (YP) high internal phase Pickering emulsions (HIPPEs) were explored as fat replacers for 3D-printed meat products. HIPPEs with varying Lyc concentrations were formulated, and their encapsulation e...

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  6. 6

    Repressor activator protein 1–promoted colorectal cell migration is associated with the regulation of Vimentin por Yongyong Yang, Chunxiang Ye, Lixin Wang, Guo An, Zhihua Tian, Lin Meng, Like Qu, Shenyi Lian, Chengchao Shou

    Publicado 2017-04-01

    Repressor activator protein 1 plays important roles in telomere protection, while repressor activator protein 1 binds to extra-telomeric DNA and exerts the function as a transcriptional regulator. Previous study showed that repressor activator protein 1 regulates the transcriptional activity of nucl...

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  7. 7

    Electro‐Acupuncture to Treat Disorder of Consciousness (AcuDoc): Study Protocol for a Randomized Sham‐Controlled Trial por Kaiqi Lin, Jixiang Chen, Jiahui Pan, Ruihong Wang, Shibiao Wu, Wanxing Wen, Yuanqing Li, Lixin Wang, Fang Yuan

    Publicado 2025-06-01

    ABSTRACT Background Treatment of disorders of consciousness (DOC) remains a clinical challenge. Electroacupuncture (EA) was shown to have the potential to promote the recovery of consciousness. This trial aims to explore the therapeutic effects and mechanisms of EA in patients with DOC due to trauma...

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  8. 8

    Supply and Demand Balance of Ecosystem Services in the Ulanbuh Desert por Weijia Cao, Xinyu Wang, Qingkang Yang, Huan Liu, Guoxiu Jia, Huamin Liu, Lixin Wang, Xuefeng Zhang, Lu Wen

    Publicado 2025-06-01

    Desert ecosystems play a critical role in global climate regulation. Current research reveals a relative lack of research regarding desert ecosystem service (ES) supply and demand. Therefore, we selected the Ulanbuh desert, one of the eight major deserts in China, as study area. Using specialized mo...

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  9. 9

    Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitors por Dongyue Jiao, Kun Chang, Jiamin Jin, Yingji Chen, Mo Ren, Yucong Zhang, Kun Gao, Yaoting Xu, Lixin Wang, Chenji Wang

    Publicado 2025-07-01

    Anti-apoptotic B-cell lymphoma-2 (BCL-2) family proteins are frequently overexpressed in various cancers, playing a pivotal role in cancer initiation and progression, as well as intrinsic or acquired resistance to therapy. Although inhibitors targeting BCL-2, such as Venetoclax, have shown efficacy...

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  10. 10

    Discovery of a novel chalcone-derived covalent Keap1 binder for mitigating cisplatin-induced mitochondrial dysfunction and nephrotoxicity por Yanyan Deng, Leizhi Xu, Zhengtao Jiang, Lin Chen, Guanghao Zhu, Chuting Xu, Xiayan Chu, Lixin Wang, Xiaoting Niu, Ling Chen, Zhangping Xiao, Jing Hu, Guangbo Ge

    Publicado 2025-09-01

    Cisplatin-induced kidney injury (CIKI) is a major adverse effect of this widely used chemotherapy agent. Targeting key events involved in CIKI, such as inflammation, apoptosis, mitochondrial dysfunction and oxidative stress, holds potential for mitigating CIKI and improving patient outcomes. Herein,...

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  11. 11

    Influences of structural helicity of aortic dissection on endovascular repair por Shi-Cheng Jin, Zi-Long Zhao, Xuyang Zhang, Peng Lv, Cheng Yan, Tiantong Xu, Jialing Yang, Lixin Wang, Zhihui Dong, Daqiao Guo, Xi-Qiao Feng, Weiguo Fu, Baolei Guo

    Publicado 2025-08-01

    Summary: Stanford type B aortic dissections often exhibit helical morphology. However, the influences of structural helicity on periprocedural and mid-to long-term adverse events after thoracic endovascular aortic repair (TEVAR) remain unclear. In this article, a total of 197 patients who underwent...

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  12. 12

    Anti-CD19 CAR-T cell therapy in relapsed/refractory t(8;21) acute myeloid leukemia with aberrant CD19 expression por Xiaomin Zhang, Xiaomin Zhang, Lixin Wang, Jingqiao Qiao, Shuhong Wang, Lijun Wang, Lian Liu, Jiading Qin, Jiading Qin, Ziren Chen, Wenfa Huang, Yuanyuan Zheng, Huixin Peng, Junhui Mei, Hongxin Wang, Chuan Yu, Yisheng Li, Yisheng Li, Li Yu

    Publicado 2025-07-01

    BackgroundT (8; 21) acute myeloid leukemia (AML) is a special type of acute leukemia, and exhibits a heterogeneous prognosis, with a long-term relapse rate of about 40%. Once t(8; 21) AML patients experience relapse, they have an extremely poor prognosis, with a 5-year overall survival rate of less...

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