Search Results - Liru Chen

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    Frailty and GLIM-defined malnutrition contribute to poor clinical outcomes in older adult inpatients in the general surgery department

    Frailty and GLIM-defined malnutrition contribute to poor clinical outcomes in older adult inpatients in the general surgery department by Chengyu Liu, Liru Chen, Peng Liu, Lei Li, Bo Cheng, Jingyong Xu, Hongyuan Cui, Mingwei Zhu

    Published 2025-06-01

    Background and aimsFrailty and malnutrition are prevalent among older adult inpatients. Our study aimed to analyze the correlation between frailty and malnutrition and determine their effects on the clinical outcomes in older adult surgical inpatients.MethodsThis cross-sectional observational study...

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  2. 2
    Moracin M derivative targeting PDE4 for the treatment of psoriasis

    Moracin M derivative targeting PDE4 for the treatment of psoriasis by Liru Chen, Deyan Wu, Sen Wang, Lingyu Wu, Youyou Chen, Baoli Li, Haibin Luo, Jian Li, Wenwen Liu

    Published 2025-02-01

    Phosphodiesterase-4 (PDE4), a member of the phosphodiesterase superfamily, has highly important roles in cyclic nucleotide signaling pathways and a variety of skin disorders. Blocking PDE4 activity with PDE4 inhibitors increases intracellular cAMP levels and effectively relieves the skin inflammator...

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