Search Results - Linlin Zhang

Steel Shear Walls (SSWs) have been utilized for years for their significant benefits. In early applications, this system was used without stiffeners, which were subsequently developed and enhanced in multiple ways. A new concept of SSWs called Flat-Corrugated Walls (FCWs) has been introduced recent...

Full description

None

Cell adhesion–mediated drug resistance is an important factor that influences the effects of chemotherapy in multiple myeloma. DTX3L, a ubiquitin ligase, plays a key role in cell-cycle-related process. Here, we found that the expression of DTX3L gradually increased during the proliferation of myelom...

Full description

Head and neck squamous cell carcinoma (HNSCC) represents the sixth most common cancer worldwide, with pathologists routinely analyzing histological slides to diagnose cancer by evaluating cellular heterogeneity, a process that remains time-consuming and labor-intensive. Although no previous studies...

Full description

Agricultural production on salinized lands is an important direction of current agricultural research. Chito-oligosaccharide has been used as an excellent soil amendment in recent years. However, the mechanism of chito-oligosaccharide composites (COS-PA) impacting cotton seedlings on salinized lands...

Full description

ABSTRACT Studies characterizing the epidemic of Mycoplasma pneumoniae (M. pneumoniae) in Henan Province are scarce. Our research investigated the epidemiological changes of M. pneumoniae and macrolide-resistant mutations of M. pneumoniae (MRMP) among children under 18 years from January 2017 to Dece...

Full description

Inorganic arsenic [As(III) and As(V)] is a pervasive environmental contaminant in groundwater systems, early-life exposure to which is associated with an impaired cognitive ability and an increased risk of neurobehavioral disorders. Although the effect of As(III) on the neurons is well studied, the...

Full description

Stem-cell-based therapies rely on the transplantation of stem cells or stem-cell-derived organotypic cells into injured tissues in order to improve or restore tissue function that has been impaired by various diseases. The potential of induced pluripotent stem cells has created many applications in...

Full description

Germline loss-of-function mutations in BRCA1 and BRCA2 (BRCA) genes are well-established as causative factors for hereditary breast and ovarian cancer (HBOC), conferring an approximately tenfold increased lifetime risk. The identification of BRCA mutations is essential for risk assessment and manage...

Full description

Cancer immunotherapy resistance significantly challenges its clinical application. Traditional immunotherapy strategies are limited by the difficulty in delivering macromolecular immune modulators into the hypoxic core of tumors, leading to reduced efficacy and the development of resistance. Recentl...

Full description