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    Dumbbell-shaped hydrogel plug for annulus fibrosus repair: From material design to in vivo validation

    Dumbbell-shaped hydrogel plug for annulus fibrosus repair: From material design to in vivo validation by Mao-dan Nie, Bing-kun Bao, Ning-ze Zhang, Rong-shan Cheng, Ling-jie Fu, Cheng-Kung Cheng

    Published 2025-07-01

    Background: Intervertebral disc (IVD) herniation is a degenerative spine disease, and current treatments often result in reherniation due to iatrogenic annulus fibrosus (AF) defects. Developing effective AF repair strategies is critical to preventing reherniation and improving surgical outcomes. Thi...

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