Search Results - Ling Chen

BackgroundInflammatory bowel disease (IBD) is a chronic autoimmune disorder driven by gut microbiota dysbiosis. As an essential immune checkpoint, Programmed death-ligand 1 (PD-L1) has been implicated in modulating gut microbiota composition. However, the precise role of PD-L1 in shaping metagenomic...

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Variations in the warm formability of AA7075 sheets are primarily attributed to differences in precipitate morphology resulting from distinct thermal histories. To better understand this relationship, this study systematically investigates the influence of precipitate characteristics—quantified by t...

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Dynamic Time Warping (DTW) is effective for subsequence matching but is limited by its high computational cost. To address this challenge, we propose a method that adaptively segments data streams and extracts Chebyshev features for piecewise approximation, enabling DTW computation in a low-dimensio...

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Organic-inorganic composite coatings have consistently garnered significant attention in corrosion protection research due to their exceptional anti-corrosion capabilities. In this study, a labyrinth-type composite coating was prepared by using the polyethersulfone (PES) as skeleton, combined with a...

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Consumers rely on sensory perception to judge the appearance of furniture, often guided by intuitive associations with shape. This process allows furniture designers to better understand and respond to consumer preferences and expectations. This work used a questionnaire design and analysis survey b...

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As the economy continues to develop rapidly, traffic volume on highways has increased dramatically, leading to increasingly severe congestion issues. In response, expanding expressways to two-way ten-lane configurations has become a mainstream strategy to alleviate traffic pressure. Given the absenc...

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IntroductionThe Anacardiaceae family, encompassing economically and ecologically significant genera such as Rhus, Mangifera, and Pistacia, exhibits substantial genomic diversity and adaptive complexity. However, comparative genomic analysis and evolutionary insights into defense-related mechanisms w...

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Intervertebral disc degeneration (IDD) is a prevalent and debilitating condition that affects millions worldwide, leading to chronic back pain and a reduced quality of life. This review shifts the focus to the pivotal role of the immune microenvironment in IDD, highlighting its dual functions—exacer...

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Aiming at the difficult problem of predicting the running state of the rotor of a Control Rod Drive Mechanism (CRDM) in a floating nuclear reactor, this paper proposes a Remaining Useful Life (RUL) prediction method based on Variational Mode Decomposition and Bidirectional Long Short-Term Memory (VM...

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BackgroundGout is caused by hyperuricemia and is associated with cardiovascular diseases. Treatment for hyperuricemia primarily involves urate-lowering medications. Some trials showed higher cardiovascular mortality rates with febuxostat compared to allopurinol in gout patients. However, data on the...

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BackgroundDiabetic retinopathy, a prevalent complication of diabetes mellitus, is a growing public health concern. The use of robust predictive models can aid healthcare professionals in identifying high-risk patients, enabling them to implement early intervention and treatment strategies.ObjectiveT...

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The lead-cooled fast reactor (LFR), a Generation IV nuclear system candidate, presents unique neutronic characteristics distinct from pressurized water reactors. Its neutron spectrum spans wider energy ranges with fast neutron dominance, exhibiting resonance phenomena across energy regions. These fe...

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This study firstly proposes and experimentally demonstrates a phase demodulation method with high sensitivity for interferometric fiber sensors (IFSs) on the basis of the fast Fourier transform of a wavenumber domain. The phase information of IFSs triggered by changes in environmental parameters is...

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This paper presents a human-in-the-loop interactive framework for skeleton-based posture recognition, designed to support model training and artistic education. A total of 4870 labeled images are used for training and validation, and 500 images are reserved for testing across five core posture categ...

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BackgroundVHL germline mutations are classically associated with von Hippel-Lindau syndrome, but their role in hematological malignancies remains underexplored.MethodsWe analyzed a pedigree with acute myeloid leukemia (AML) proband and two offspring: primary immune thrombocytopenia (ITP) and acute T...

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The incidence rate of intrahepatic cholangiocarcinoma is rising, and treatment options are limited. Therefore, new biological markers of intrahepatic cholangiocarcinoma are needed. Immunohistochemistry and enzyme-linked immunosorbent assay were applied to analyze the expressions of CD97, CD55, and s...

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With the development and application of artificial intelligence (AI) technology, autonomous driving systems are gradually being applied on the road. However, people still have requirements for the safety and reliability of unmanned vehicles. Autonomous driving systems in today’s unmanned vehicles al...

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In order to precisely assess gene expression level, a suitable internal reference gene must be chosen to quantify real-time reverse transcription polymerase chain reaction (RT-qPCR) data. For greenbug, Schizaphis graminum, a suitable reference gene for assessing the level of transcriptional expressi...

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ObjectiveThis study aims to elucidate the relationship between canopy structure and fruit spatial distribution, establish a model linking canopy light distribution with fruit positioning, and identify optimal training strategies for consistently high yield. The findings provide a theoretical foundat...

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High yield in rice mainly depends on large grain weight, ideal plant architecture and proper flowering time adapting to various geographic regions. To help achieve higher yield, phenotype variations of heading date (HD), plant architecture and grain shape in a panel of 416 rice accessions were inves...

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