Torthaí cuardaigh - Lin Ma

We propose a birefringence variation independent fiber-optic current sensor based on polarization diversity and a real-time state of polarization measurement technique. We theoretically and experimentally demonstrate the compensation for the degradation of Faraday effect due to the variation in bire...

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In underwater visible light communication (UVLC) systems, it is important to support mobility of transceivers and enhance both the dynamic range of communication distance and the field of view (FOV) because the received optical power experiences significant variations when the transmission distance...

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We demonstrate the design and fabrication of a mode (de)multiplexer based on the tapered mode-selective coupler. The proposed device is directly inscribed in the substrate material by a needle-type liquid micro-dispenser and a three-axis robot stage using commercially available UV-curable resins. Th...

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Background Azithromycin, a widely prescribed macrolide antibiotic, faces emerging safety concerns due to inappropriate use and age-specific adverse drug reactions (ADRs). This study characterises age-stratified safety profiles of azithromycin using pharmacovigilance data.Methods Adverse event (AE) r...

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Abstract Background The association between family socioeconomic status (SES) and adolescent well-being is complex, involving both present and future dimensions. This study examines perceived discrimination as a mediator in this association and grit as a potential moderator buffering the adverse eff...

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In the operation of a power distribution system, miniature circuit breakers (MCBs) are subjected to the synergistic effect of electrical and mechanical stresses in service, and their operational performance is progressively degraded, which is prone to bring significant losses to the users after fail...

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This study evaluated adverse events reported with tirzepatide, a dual GIP/GLP-1 receptor agonist approved for type 2 diabetes and obesity, using real-world data from the FDA Adverse Event Reporting System. A disproportionality analysis was conducted on reports from May 2022 to the fourth quarter of...

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Worldwide cancer mortality rates underscore the pressing need to identify and develop novel anticancer therapies to supplement traditional cancer treatments. Naturally occurring bacteria are ideal for cancer therapy owing to their autonomous propulsion and hypoxia-targeting properties, but their poo...

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IntroductionEmotion recognition based on electroencephalogram (EEG) signals has shown increasing application potential in fields such as brain-computer interfaces and affective computing. However, current graph neural network models rely on predefined fixed adjacency matrices during training, which...

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BackgroundBronchial asthma (asthma) is a chronic inflammatory disease of the airways, involving a variety of cells and cellular components, that manifests clinically as recurrent episodes of wheezing, shortness of breath, with or without chest tightness or cough, airway hyperresponsiveness, and vari...

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1G, a novel derivative of curcumin, exhibits promising anticancer activities in various cancer cell lines. To support its further pharmacological studies, a liquid chromatography–tandem mass spectrometry method was developed and validated in accordance with FDA's Guidance. After extraction by p...

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ABSTRACT TBC1 Domain Family Member 1 (TBC1D1) plays a crucial role in various cancers. However, its specific function in pancreatic cancer (PC) remains poorly understood. In this study, we aimed to evaluate the prognostic value of TBC1D1 and its correlation with the tumor microenvironment (TME) in P...

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We studied the characteristics of coupled-core four-core fibers (CC-4CFs) with different core pitches both theoretically and experimentally. The spatial mode dispersions of different fibers were analyzed, and the result agrees well with theoretical ones. In the experiment, we achieved a spatial mode...

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The forest canopy height (FCH) is a crucial indicator of ecosystem processes, significantly influencing biomass distribution and biodiversity. Accurately and efficiently obtaining large-scale FCH information is vital for monitoring forest health and carbon storage. However, current research and prod...

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Background Neoadjuvant immune checkpoint blockade (nICB) has revolutionized cancer treatment, yet the underlying mechanisms of resistance in bladder cancer remain to be explored.Methods We conducted single-cell RNA sequencing (scRNA-seq) on peripheral blood mononuclear cells, tumor tissues, adjacent...

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A particle size inversion method based on whale optimization algorithm (WOA) is presented. In the experiment, the small angle forward scattering measurement system is used to conduct experimental research on the inversion of bubble particle size. WOA is used to invert and simulate the bubbles that f...

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Background: Kidney transplantation is the most effective treatment for end-stage kidney disease. However, delayed graft function (DGF) remains a common complication. Roxadustat effectively treats renal anemia and ameliorates acute kidney injury. However, its efficacy in kidney transplant recipients...

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Purpose: To investigate the correlation of serum uric acid levels with the clinical outcomes of arthroscopic microfracture in osteochondral lesions of the talus (OLTs) and determine the cut-off point for predicting outcomes. Methods: A total of 134 OLTs patients who underwent arthroscopic microfract...

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