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    Combined effects of Yupingfeng and metformin on blood glucose levels and intestinal tissue in high-fat diet-induced type 2 diabetic rats

    Combined effects of Yupingfeng and metformin on blood glucose levels and intestinal tissue in high-fat diet-induced type 2 diabetic rats by Hui Liu, Hui Liu, Yuan Guan, Like Xu, Ji Hu, Ji Hu

    Published 2025-07-01

    This study investigated the effectiveness of a high-fat diet (HFD) in inducing type 2 diabetes in Sprague–Dawley (SD) rats and evaluated the combined therapeutic effects of Yupingfeng and metformin on glycemic index and intestinal histology. A total of 60 SD rats, equally divided by sex, were random...

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    Building bridges to operationalize One Health — A longitudinal two years’ AMR study in England using clinical and wastewater-based surveillance approaches

    Building bridges to operationalize One Health — A longitudinal two years’ AMR study in England using clinical and wastewater-based surveillance approaches by Like Xu, Nicola Ceolotto, Kishore Jagadeesan, Richard Standerwick, Megan Robertson, Ruth Barden, Helen Lambert, Barbara Kasprzyk-Hordern

    Published 2025-06-01

    ABSTRACT: Objectives: The coronavirus disease 2019 (COVID-19) pandemic impacted antimicrobial resistance (AMR) in clinical settings, but evidence is lacking. Considering this, we evaluated community-wide AMR in the shadow of COVID-19, using wastewater-based epidemiology (WBE). Methods: Five hundred...

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