Search Results - Ligen Lin

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    Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review

    Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review by Cheng Chen, Zheling Feng, Jovana Petrović, Marina Soković, Yang Ye, Ligen Lin

    Published 2023-08-01

    Inflammation is an essential part of the immune response to injury and infection. Emerging evidence indicates that long-term low-grade inflammation is positively correlated with many diseases, such as cancer, metabolic disorders, and cardiovascular diseases. Due to common anti-inflammatory drugs are...

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    G protein-coupled receptor-biased signaling: potential drug discovery to facilitate treatment of metabolic diseases

    G protein-coupled receptor-biased signaling: potential drug discovery to facilitate treatment of metabolic diseases by Shengnan Shen, Qiwen Liao, Liwei Gu, Yongping Zhu, Yanqing Liu, Xinwei Zhang, Junzhe Zhang, Qiaoli Shi, Yuxiang Sun, Jigang Wang, Ligen Lin

    Published 2024-02-01

    G protein-coupled receptors (GPCRs) are important, potential drug targets for the treatment of metabolic disorders, such as obesity. GPCRs crosstalk with several transducers, including heterotrimeric G proteins, GPCR kinases (GRKs), and β-arrestins. GPCR-biased agonism has raised the potential of no...

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