Resultados de búsqueda - Libo Zhao
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STING agonist delivery by lipid calcium phosphate nanoparticles enhances immune activation for neuroblastoma
Publicado 2023-05-01Enlace del recursoNeuroblastoma (NB) is a common solid tumor in children and infants, the formation and regression of which is closely linked to the tumor-host immune relationship. Stimulator of interferon genes (STING) agonists, particularly cyclic dinucleotide (CDN), have promising potential in NB therapy by genera...
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Push Forward Clinical Management of Hematological Toxicity due to Lenalidomide Overexposure: Model‐Informed Precision Dosing for Chinese Population With Renal Insufficiency
Publicado 2025-07-01Enlace del recursoABSTRACT Dose‐dependent hematological toxicity of lenalidomide has been reported previously, and thus, there is a clinical need for dose individualization to manage toxicities. The objectives of this study were to explore optimal individualized dosing regimens for Chinese B‐cell malignancies patient...
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Effect of obstructive sleep apnoea syndrome combined with renal insufficiency on all-cause mortality in elderly patients in China: a prospective cohort study
Publicado 2025-07-01Enlace del recursoObjective We hypothesised that all-cause mortality in elderly patients with obstructive sleep apnoea syndrome (OSAS) was associated with renal insufficiency.Design A cohort study.Setting A prospective study of patients with OSAS enrolled in sleep centres/departments in multicentre hospitals in China...
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Determination of Main Bearing Dynamic Clearance in a Shield Tunneling Machine Through a Broadband PMUT Array with a Decreased Blind Area and High Accuracy
Publicado 2025-07-01Enlace del recursoTraditional PMUT ultrasonic ranging systems usually possess a large measurement blind area under the integrated transmit–receive mode, dramatically limiting its distance measurement in confined spaces, such as when determining the clearance of large bearing components. Here, a broadband PMUT rangefi...
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Structural Optimization Design of the Dual-Layer CMUT with Low Power Consumption and High Ultrasonic Reception Performance
Publicado 2025-06-01Enlace del recursoCapacitive micromachined ultrasonic transducers (CMUTs) have been widely applied in fields such as air-coupled ultrasonic nondestructive testing, gesture recognition, and 3D imaging. However, most current CMUTs struggle to simultaneously achieve both low power consumption and high performance, which...
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Research on Drive and Detection Technology of CMUT Multi-Array Transducers Based on MEMS Technology
Publicado 2025-05-01Enlace del recursoThis paper presents an ultrasonic driving and detection system based on a CMUT array using MEMS technology. Among them, the core component CMUT array is composed of 8 × 8 CMUT array elements, and each CMUT array element contains 6 × 6 CMUT units. The collapse voltage of a single CMUT unit obtained t...
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State of the Art of Low‐Frequency Acoustic Modulation: Intensity Enhancement and Directional Control
Publicado 2025-07-01Enlace del recursoAbstract High‐intensity low‐frequency acoustic sources with directivity play a significant role in various fields such as medical treatment, underwater communication, and environmental monitoring. However, the long wavelengths, strong penetration, and their tendency to easily diffract of low‐frequen...
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