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A lethal juvenile mouse model for the evaluation of antiviral reagents against coxsackievirus A4 由 Qin Su, Xiao Chen, Zhihui Zheng, Hailin Wei, Jiaxue Zhou, Libing Zhang, Ali Muhammad, Yin Wang, Xiang Chen, Pinghu Zhang
出版 2025-08-01Summary: Coxsackievirus A4 (CVA4) as a pathogen causing severe herpangina has become global outbreak epidemics during the past 5 years. However, there is currently no effective vaccines and drugs available. Here, one mouse-adapted CVA4 virus (YZ08) was cultivated by repeatedly cross-passaging betwee...
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