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    Antisense oligonucleotides targeting IRF4 alleviate psoriasis

    Antisense oligonucleotides targeting IRF4 alleviate psoriasis by Yanxia Yu, Yirui Wang, Weiwei Chen, Chang Zhang, Zhuo li, Jing Yu, Minhao Wang, Can Song, Sihao Yan, Jiayi Lu, Liangdan Sun

    Published 2025-07-01

    Interferon regulatory factor 4 (IRF4) is a critical transcription factor that governs the differentiation of cluster of differentiation 4+ (CD4+) T cells. The pathogenesis and progression of psoriasis are primarily attributed to an immune imbalance stemming from the overproduction of interleukin-17A...

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