Search Results - Li-yang ZHANG
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Analysis of key immune-related genes and drug candidates in globoid cell leukodystrophy
Published 2025-06-01Get full textObjective To identify the key immune-related genes and potential drug targets of Krabbe disease by using neural stem cells(NSCs) derived from induced pluripotent stem cells(iPSCs) generated from patients with Krabbe disease. Methods 1)The transcriptome data of GLD-NSCs(GSE212512) was analyzed using...
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Relative bioavailability of tribasic zinc sulfate for broilers fed a conventional corn-soybean meal diet
Published 2015-10-01Get full textAn experiment was carried out to investigate the relative bioavailability of tribasic zinc (Zn) sulfate relative to Zn sulfate for broilers fed a conventional corn-soybean meal diet. A total of 504 1-d-old Arbor Acres commercial male chicks were randomly assigned by body weight of birds to one of se...
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Effect of dietary supplementation with flavonoid from Scutellaria baicalensis Georgi on growth performance, meat quality and antioxidative ability of broilers
Published 2018-05-01Get full textAn experiment was conducted to investigate the effect of dietary supplementation with flavonoid from Scutellaria baicalensis Georgi (SBGFN) as SBGFN-zinc (SBGFN-Zn) on growth performance, meat quality, immune responses and antioxidation of broilers. A total of 450 one-d-old Arbor Acres male broilers...
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Manganese enhances the expression of the manganese superoxide dismutase in cultured primary chick embryonic myocardial cells
Published 2017-09-01Get full textIn the present study, the effect of manganese (Mn) on antioxidant status and the expression of the manganese superoxide dismutase (MnSOD) gene in cultured primary myocardial cells collected from the chick embryos was investigated. The hypothesis that Mn supplementation would enhance the expression o...
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Effect of in ovo zinc injection on the embryonic development, tissue zinc contents, antioxidation, and related gene expressions of broiler breeder eggs
Published 2018-03-01Get full textTwo experiments were conducted to investigate the effect of in ovo zinc (Zn) injection on the embryonic development, tissue Zn contents, antioxidation and related gene expressions of fertilized eggs of Arbor Acres broiler breeders. Experiment 1 was conducted to determine an optimal embryonic age for...
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Effects of dietary graded levels of cinnamon essential oil and its combination with bamboo leaf flavonoid on immune function, antioxidative ability and intestinal microbiota of bro...
Published 2019-09-01Get full textCinnamon essential oil (CEO) and its combination with bamboo leaf flavonoid (BLF) have been shown to exhibit an additive antibacterial effect in vitro, but their functions in broilers were not clear. An experiment was conducted to investigate the effects of dietary graded levels of CEO and its combi...
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Effect of the gene silencing of phosphorus transporters on phosphorus absorption across primary cultured duodenal epithelial cell monolayers of chick embryos
Published 2022-07-01Get full textThe aim of the study was to investigate whether phosphorus (P) transporters, type IIb sodium-dependent phosphate cotransporter (NaP-IIb) and inorganic phosphate transporter 2 (PiT2), were directly involved in P absorption across primary cultured duodenal epithelial cell monolayers of chick embryos....
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Effectiveness of dietary xylo-oligosaccharides for broilers fed a conventional corn-soybean meal diet
Published 2015-10-01Get full textAn experiment was conducted to investigate the effect of dietary supplementation of xylo-oligosaccharides (XOS) on growth performance, meat quality, immune functions, duodenal morphology and intestinal microbial populations of broilers fed a conventional corn-soybean meal basal diet. A total of 450...
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Effects of selenium source and level on growth performance, antioxidative ability and meat quality of broilers
Published 2021-01-01Get full textThis experiment was conducted to investigate the effects of selenium (Se) source and level on growth performance, carcass traits, antioxidative ability and meat quality of broilers. A total of 320 one-d-old Arbor Acres commercial broilers were randomly assigned to 1 of 5 treatments with 8 replicates...
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Effect of dietary calcium or phosphorus deficiency on bone development and related calcium or phosphorus metabolic utilization parameters of broilers from 22 to 42 days of age
Published 2020-11-01Get full textThis experiment was conducted to investigate the effect of dietary calcium (Ca) or phosphorus (P) deficiency on bone development and related Ca or P metabolic utilization parameters of broilers from 22 to 42 days of age based on our previous study, which indicated that dietary Ca or P deficiency imp...
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Effect of dietary supplementation of pyrroloquinoline quinone disodium on growth performance, meat quality and antioxidative ability of broilers
Published 2020-07-01Get full textThis study was conducted to investigate the effect of dietary supplementation with pyrroloquinoline quinone (PQQ) in the form of PQQ disodium (PQQ▪Na2) on the growth performance, carcass traits, meat quality and antioxidative ability of broilers. A total of 720 one-d-old Arbor Acres male broilers we...
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Regulation of bone phosphorus retention and bone development possibly by BMP and MAPK signaling pathways in broilers
Published 2022-10-01Get full textThe bone morphogenetic protein (BMP) and mitogen-activated protein kinase (MAPK) signaling pathways play an important role in regulation of bone formation and development, however, it remains unclear that the effect of dietary different levels of non-phytate phosphorus (NPP) on these signaling pathw...
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Kinetics of selenium absorption in ligated small intestinal loops of chicks
Published 2020-08-01Get full textSelenium (Se) is an essential trace element that has a large number of biological functions for broilers. However, the absorption kinetics of Se from sodium selenite in the small intestine of broilers remains unclear. Therefore, two experiments were conducted with 28-d-old commercial male broilers t...
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Establishment and evaluation of the primary cultured tibial osteoblast model of broiler chicks
Published 2023-02-01Get full textOsteoblasts are considered as a major factor contributing to bone development and mineralization, however, few studies have been done to establish and evaluate the primary cultured tibial osteoblast model of broiler chicks. Therefore, in the present study, two experiments were conducted to establish...
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