Search Results - Li Tan
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Deferoxamine therapy for intracerebral hemorrhage: A systematic review.
Published 2018-01-01Get full textIntracerebral hemorrhage (ICH) is a significant cause of morbidity and mortality worldwide. Several recent controlled trials have reported that deferoxamine (DFX) therapy appears to be effective for ICH. The aim of this study was to perform a systematic review of DFX therapy for ICH patients and eva...
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Echocardiography interpretation training and internal medicine milestones: A pilot study
Published 2025-07-01Get full textBackground/Purpose: The competency-based Internal Medicine Milestones (IMM) assesses physician training outcomes through six key competencies. This pilot study introduced IMM concepts through an echocardiography report interpretation course for postgraduate students (PGYs) and residents (Rs). We aim...
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Modulating the electronic state of Cu over Cu/ZnO/SBA-15 catalysts for boosting methanol synthesis from CO2
Published 2025-06-01Get full textMethanol synthesis via CO2 conversion is a “green carbon” route for mitigating the greenhouse effect and recycling carbon resources. However, despite the widespread use of copper-based systems for methanol synthesis in recent decades, the chemical state of the active Cu species remains controversial...
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Long Chain Acyl-Coenzyme A Synthetase 4 (BnLACS4) Gene from Brassica napus Enhances the Yeast Lipid Contents
Published 2014-01-01Get full textLong-chain acyl-Coenzyme A (CoA) synthetases (LACSs) catalyze the formation of long-chain acyl-CoA, and play important roles in fatty acid metabolism including phospholipids, triacylglycerol (TAG) biosynthesis and fatty acid β-oxidation. Here, we report the characterization of a LACS gene from Brass...
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Cone beam CT for paranasal sinus and temporal bone: A cost-benefit analysis in Singapore
Published 2025-05-01Get full textCone beam computed tomography (CBCT) has emerged as a valuable imaging tool in Otorhinolaryngology or the specialty of ear, nose and throat (ENT), where precise imaging of the sinus and temporal bone pathologies is essential. This paper presents a cost-benefit analysis (CBA) of CBCT in a public hea...
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Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study
Published 2025-07-01Get full textBackgroundPeripheral immune cells can predict responses to immune checkpoint inhibitor (ICI) therapy, but their relationship with early ICI-associated cardiovascular adverse events (CVAEs) is unclear. This study aimed to assess the predictive value of peripheral immune cells in early ICI-associated...
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The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy
Published 2025-07-01Get full textIntroductionImmunoglobulin A nephropathy (IgAN) and membranous nephropathy (MN) are among the most common forms of primary glomerular diseases, with a rising global incidence. Despite their clinical importance, the underlying pathogenesis of these diseases and the development of reliable non-invasiv...
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Refractory Chylothorax in a Patient With Severe Mitral Regurgitation
Published 2025-06-01Get full textABSTRACT We report a case of chylothorax secondary to severe mitral regurgitation, in the absence of heart failure with a low ejection fraction. A 49‐year‐old male presented with mitral valve infective endocarditis, complicated by severe mitral regurgitation with persistent vegetations 5 weeks into...
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RACK7 senses and fine-tunes enhancer activity
Published 2025-08-01Get full textSummary: Enhancers regulate dynamic gene expression in a spatiotemporal specific manner. A number of positive as well as negative regulators of enhancers have been reported so far. However, whether and how these regulators sense enhancer activity dynamics remains unclear. In this study, we show that...
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