Search Results - Li Ding
Li Ding
Li Ding is the David English Smith Distinguished Professor of Medicine at Washington University School of Medicine. She is known for the development of multiple computational tools now commonly used in cancer biology research, including VarScan, HotSpot3D, and BreakDancer. Provided by Wikipedia-
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Optimization of software project evaluation system
Published 2020-06-01Get full textStarting from the problems of imperfect evaluation index system, non-standard evaluation method and single factor of performance evaluation model, this paper applies the unified grey clustering analysis algorithm to establish the index system of software organization status and software project cha...
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Sleep Snoring Sound Recognition Based on Wavelet Packet Transform
Published 2023-03-01Get full textSnoring is a typical and intuitive symptom of the obstructive sleep apnea hypopnea syndrome (OSAHS), which is a kind of sleep-related respiratory disorder having adverse effects on people’s lives. Detecting snoring sounds from the whole night recorded sounds is the first but the most important step...
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Pharmacokinetics, Safety, and Tolerability of (R)-Ketamine Hydrochloride Injection, a Novel Rapid-Acting Antidepressant, in Healthy Chinese Subjects
Published 2025-07-01Get full text<b>Objectives</b>: (R)-ketamine hydrochloride injection is a novel, rapid-acting antidepressant for the treatment of treatment-resistant depression. The aim of this study was to assess the pharmacokinetics, safety, and tolerability of (R)-ketamine hydrochloride injection in healthy Chine...
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Thiacloprid Exposure Induces Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis in the Liver of Mauremys reevesii
Published 2025-02-01Get full textABSTRACT Among neonicotinoid insecticides, thiacloprid (THI) is extensively utilized in agricultural practices, which poses a potential toxicity risk to aquatic fauna. Turtles, integral to aquatic ecosystems, have not yet been comprehensively assessed for their vulnerability to THI exposure. In this...
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Snoring Sounds Classification of OSAHS Patients Based on Model Fusion
Published 2025-02-01Get full textObstructive sleep apnea hypopnea syndrome (OSAHS) is a prevalent and detrimental chronic condition. The conventional diagnostic approach for OSAHS is intricate and costly. Snoring is one of the most typical and easily obtained symptom of OSAHS patients. In this study, a series of acoustic features a...
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Caffeinated chewing gum produces comparable strength and power gains to capsules with fewer side effects in resistance-trained men
Published 2025-12-01Get full textBackground Caffeine, widely used as an ergogenic aid, has been extensively studied regarding its dosage and timing of ingestion. However, the impact of different administration methods on caffeine’s performance-enhancing effects remains relatively underexplored. This study compared the effects of ca...
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Promising therapeutic role of miR-27b in tumor
Published 2017-03-01Get full textMicroRNAs are small nonprotein-encoding RNAs ranging from 18 to 25 nucleotides in size and regulate multiple biological pathways via directly targeting a variety of associated genes in cancers. MicroRNA-27b is a highly conserved MicroRNA throughout vertebrates and there are two homologs (hsa-miR-27a...
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Influence of Wind Speed in Painting Room on the Uniformity of Paint Film
Published 2021-10-01Get full textThe painting process using electrostatic rotating bell - cup is the current mainstream of automotive painting process. In order to ensure that the concentration of VOCs (Volatile Organic Compounds) gas in painting room is lower than its lower explosive limit, an exhaust system will be used to keep t...
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Molecular Characterization of Anaplasma , Ehrlichia, Babesia , and Borrelia in Ticks from Guangdong Province of Southern China
Published 2023-06-01Get full textTick-borne pathogens have become emerging global health threats in humans and animals. The objective of the present study was to investigate Anaplasma, Ehrlichia, Babesia , and Borrelia in ticks in southern China. Ticks were collected from animals and identified to the species level. Tick-borne...
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Assessment of Risk of Establishment of Wheat Dwarf Bunt (Tilletia controversa) in China
Published 2013-01-01Get full textWheat dwarf bunt, caused by Tilletia controversa Kühn (TCK), is an important quarantine wheat disease throughout the world. Based on published research results of the biology and the epidemiology of the disease, the main factors including temperature, humidity, snow cover, and their parameters relat...
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Functional characterization of a common XIa inhibitory Kunitz-domain Shp4 from nine schistosoma secreted proteins with diverse C-terminal fragments.
Published 2025-07-01Get full textCoagulation factor XIa is a drug target for new anticoagulants, but no XIa inhibitors have been found from schistosoma, a worm living in the bloodstream. In this study, by sequence blasting and structural fold searching of Kunitz-domain containing proteins from schistosoma, a specific Kunitz-domain...
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FpPDE1 function of Fsarium pseudograminearum on pathogenesis in wheat
Published 2017-11-01Get full textWheat crown rot caused by Fusarium spp. is a common disease worldwide. Both Fusarium pseudograminearum and Fusarium graminearum infect wheat crown and produce mycotoxin leading to grain loss due to white head. F. pseudograminearum (Fp) was reported in wheat from Henan Province of China a couple of y...
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CRISPRi screen of long non-coding RNAs identifies LINC03045 regulating glioblastoma invasion.
Published 2024-06-01Get full text<h4>Introduction</h4>Glioblastoma (GBM) invasion studies have focused on coding genes, while few studies evaluate long non-coding RNAs (lncRNAs), transcripts without protein-coding potential, for role in GBM invasion. We leveraged CRISPR-interference (CRISPRi) to evaluate invasive functi...
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