Search Results - Li Ding

Li Ding

Li Ding is the David English Smith Distinguished Professor of Medicine at Washington University School of Medicine. She is known for the development of multiple computational tools now commonly used in cancer biology research, including VarScan, HotSpot3D, and BreakDancer. Provided by Wikipedia
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  1. 1

    Optimization of software project evaluation system by Li ding .

    Published 2020-06-01

    Starting from the problems of imperfect evaluation index system, non-standard evaluation method and single factor of performance evaluation model, this paper applies the unified grey clustering analysis algorithm to establish the index system of software organization status and software project cha...

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  2. 2

    Sleep Snoring Sound Recognition Based on Wavelet Packet Transform by Li Ding, Jianxin Peng, Xiaowen Zhang, Lijuan Song

    Published 2023-03-01

    Snoring is a typical and intuitive symptom of the obstructive sleep apnea hypopnea syndrome (OSAHS), which is a kind of sleep-related respiratory disorder having adverse effects on people’s lives. Detecting snoring sounds from the whole night recorded sounds is the first but the most important step...

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  3. 3

    Pharmacokinetics, Safety, and Tolerability of (R)-Ketamine Hydrochloride Injection, a Novel Rapid-Acting Antidepressant, in Healthy Chinese Subjects by Rui Wang, Yuqian Yang, Tong Zhou, Bingjie Zou, Li Ding

    Published 2025-07-01

    <b>Objectives</b>: (R)-ketamine hydrochloride injection is a novel, rapid-acting antidepressant for the treatment of treatment-resistant depression. The aim of this study was to assess the pharmacokinetics, safety, and tolerability of (R)-ketamine hydrochloride injection in healthy Chine...

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  4. 4

    Thiacloprid Exposure Induces Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis in the Liver of Mauremys reevesii by Shuqin Lin, Yunjuan Xiao, Siyu Li, Liyan Tang, Haitao Shi, Meiling Hong, Li Ding

    Published 2025-02-01

    ABSTRACT Among neonicotinoid insecticides, thiacloprid (THI) is extensively utilized in agricultural practices, which poses a potential toxicity risk to aquatic fauna. Turtles, integral to aquatic ecosystems, have not yet been comprehensively assessed for their vulnerability to THI exposure. In this...

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  5. 5

    Snoring Sounds Classification of OSAHS Patients Based on Model Fusion by Yexin LUO, Jianxin PENG, Li DING, Yikai ZHANG, Lijuan SONG, Qianfan ZHANG, Houpeng CHEN

    Published 2025-02-01

    Obstructive sleep apnea hypopnea syndrome (OSAHS) is a prevalent and detrimental chronic condition. The conventional diagnostic approach for OSAHS is intricate and costly. Snoring is one of the most typical and easily obtained symptom of OSAHS patients. In this study, a series of acoustic features a...

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  6. 6

    Caffeinated chewing gum produces comparable strength and power gains to capsules with fewer side effects in resistance-trained men by Li Ding, Jue Liu, Yixuan Ma, Litian Bai, Li Guo, Bin Chen, Yinhang Cao, Olivier Girard

    Published 2025-12-01

    Background Caffeine, widely used as an ergogenic aid, has been extensively studied regarding its dosage and timing of ingestion. However, the impact of different administration methods on caffeine’s performance-enhancing effects remains relatively underexplored. This study compared the effects of ca...

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  7. 7

    Promising therapeutic role of miR-27b in tumor by Li Ding, Jie Ni, Fan Yang, Lingli Huang, Heng Deng, Yang Wu, Xuansheng Ding, Jinhai Tang

    Published 2017-03-01

    MicroRNAs are small nonprotein-encoding RNAs ranging from 18 to 25 nucleotides in size and regulate multiple biological pathways via directly targeting a variety of associated genes in cancers. MicroRNA-27b is a highly conserved MicroRNA throughout vertebrates and there are two homologs (hsa-miR-27a...

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  8. 8

    Influence of Wind Speed in Painting Room on the Uniformity of Paint Film by XU Hong - peng, ZOU Hui, WANG Jing - shuai, LI Ding - ding, PANG Mao - fei, ZHANG Mei - rong

    Published 2021-10-01

    The painting process using electrostatic rotating bell - cup is the current mainstream of automotive painting process. In order to ensure that the concentration of VOCs (Volatile Organic Compounds) gas in painting room is lower than its lower explosive limit, an exhaust system will be used to keep t...

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  9. 9

    Molecular Characterization of Anaplasma , Ehrlichia, Babesia , and Borrelia in Ticks from Guangdong Province of Southern China by Li Zhang, Zhengkai Wei, Li Ding, Jiaming Hou, Jianhui Zhang, Bohan Zhang, Jun Ma, Mingxin Song, Quan Liu

    Published 2023-06-01

    Tick-borne pathogens have become emerging global health threats in humans and animals. The objective of the present study was to investigate Anaplasma, Ehrlichia, Babesia , and Borrelia in ticks in southern China. Ticks were collected from animals and identified to the species level. Tick-borne...

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  10. 10

    Assessment of Risk of Establishment of Wheat Dwarf Bunt (Tilletia controversa) in China by Wen-mmg JIA, Yi-lin ZHOU, Xia-yu DUAN, Yong LUO, Sheng-li DING, Xue-ren CAO, D L Fitt Bruce

    Published 2013-01-01

    Wheat dwarf bunt, caused by Tilletia controversa Kühn (TCK), is an important quarantine wheat disease throughout the world. Based on published research results of the biology and the epidemiology of the disease, the main factors including temperature, humidity, snow cover, and their parameters relat...

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  11. 11

    Functional characterization of a common XIa inhibitory Kunitz-domain Shp4 from nine schistosoma secreted proteins with diverse C-terminal fragments. by Xiangdong Ye, Xiaolin Deng, Huanhuan Gao, Shuwen Chen, Li Ding, Fang Sun, Chenhu Qin, Hongyi Luo, Wen Zhu, Xudong Luo, Zongyun Chen

    Published 2025-07-01

    Coagulation factor XIa is a drug target for new anticoagulants, but no XIa inhibitors have been found from schistosoma, a worm living in the bloodstream. In this study, by sequence blasting and structural fold searching of Kunitz-domain containing proteins from schistosoma, a specific Kunitz-domain...

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  12. 12
  13. 13

    FpPDE1 function of Fsarium pseudograminearum on pathogenesis in wheat by Li-min WANG, Yi-fan ZHANG, Zhen-lin DU, Rui-jiao KANG, Lin-lin CHEN, Xiao-ping XING, Hongxia YUAN, Sheng-li DING, Hong-lian LI

    Published 2017-11-01

    Wheat crown rot caused by Fusarium spp. is a common disease worldwide. Both Fusarium pseudograminearum and Fusarium graminearum infect wheat crown and produce mycotoxin leading to grain loss due to white head. F. pseudograminearum (Fp) was reported in wheat from Henan Province of China a couple of y...

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  14. 14

    CRISPRi screen of long non-coding RNAs identifies LINC03045 regulating glioblastoma invasion. by Kathleen Tsung, Kristie Q Liu, Jane S Han, Krutika Deshpande, Tammy Doan, Yong-Hwee Eddie Loh, Li Ding, Wentao Yang, Josh Neman, Yali Dou, Frank J Attenello

    Published 2024-06-01

    <h4>Introduction</h4>Glioblastoma (GBM) invasion studies have focused on coding genes, while few studies evaluate long non-coding RNAs (lncRNAs), transcripts without protein-coding potential, for role in GBM invasion. We leveraged CRISPR-interference (CRISPRi) to evaluate invasive functi...

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