Search Results - Lei Wan
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Mechanistic and therapeutic insights into the function of different cell death modalities in rheumatoid arthritis: emphasis on the crosstalk with non-coding RNAs
Published 2025-07-01Get full textRheumatoid arthritis (RA), a prevalent autoimmune disorder, imposes a substantial burden on global health due to its progressive disability and compromised patient well-being. Although the precise etiology of this condition is still not fully understood, current research implicates intricate interac...
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Exosome circ-CBLB promotes M1 macrophage polarization in rheumatoid arthritis through the TLR3/TRAF3 signaling axis
Published 2025-07-01Get full textBackgroundRheumatoid arthritis (RA) is a chronic autoimmune condition characterized by persistent inflammation of the joint’s synovial membrane. This inflammation leads to the degradation of joint cartilage and bone, resulting in joint dysfunction and deformity. Early symptoms of RA are often subtle...
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Uniaxial tensile material properties of adult Chinese dura mater: investigating the influence of age, sex, and anatomical site
Published 2025-07-01Get full textObjectiveThis study investigated the biomechanical properties of the dura mater from 29 Chinese adult donors (20 -86 years), focused on the influence of age, anatomical region, sex and loading direction, to establish Chinese population - specific material parameters for cranial finite element (FE) m...
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Effects of a 24-week yoga intervention on choriocapillaris density in Parkinson’s disease
Published 2025-01-01Get full textIntroduction: Parkinson’s disease (PD) involves systemic microvascular dysfunction, with choriocapillaris density (CCD) potentially reflecting it. This study examined whether a 24-week yoga intervention alters CCD in PD and whether responses differ by disease duration, severity, or intervention styl...
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Interfacial tuning of magnetic anisotropy for low-power spintronic memory devices
Published 2025-06-01Get full textInterfacial engineering of magnetic anisotropy is crucial for the development of low-power spintronic memory devices. In thin-film magnetic heterostructures, perpendicular magnetic anisotropy (PMA) supports high-density data storage by reducing device dimensions while maintaining thermal stability a...
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Pseudo-binary reactive synthesis of porous multi-component alloys
Published 2025-07-01Get full textPorous multicomponent alloys, as pivotal functional materials, hold great promise for applications in environmental protection and energy conversion fields. In order to address the challenges posed by powder moldability, fast sintering, composition control and pore-structure regulation of porous mul...
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Exploring the potential anti-apoptotic effects of traditional Chinese medicine in intervertebral disc degeneration: mechanisms and therapeutic prospects
Published 2025-08-01Get full textIntervertebral disc degeneration (IDD) stands as one of the primary culprits behind low back pain and disability, imposing substantial burdens on individual health, families, and societal wellbeing. The multifactorial etiology and complex pathology of IDD pose significant challenges, with molecular...
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Harnessing Lactiplantibacillus plantarum EP21 and its membrane vesicles to inhibit myopia development
Published 2025-12-01Get full textLactiplantibacillus plantarum, a probiotic that is frequently found in fermented foods, is well known for its numerous health-enhancing properties. This study explored the potential of Lactiplantibacillus plantarum EP21 and its membrane vesicles (MVs) in mitigating myopia progression. In animal mode...
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