Search Results - Lei Shen

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  1. 1

    Analysis of the molecular subtypes and prognostic models of anoikis-related genes in colorectal cancer by Lei Shen, Kang Hou, Jifeng Zhang, Xiaodong Li

    Published 2025-06-01

    BackgroundColorectal cancer (CRC) is a malignant tumor originating from the epithelial cells of colon or rectum. Currently, the main treatment strategy is surgery with chemotherapy and radiotherapy, but the 5-year survival rate is only 63%. Therefore, new therapeutic targets should be discovered and...

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  2. 2

    Blind Recognition Algorithm of Multi-Carrier Composite Modulation Signal Based on Multi-Dimensional Time-Frequency Superimposed Spectrum by Shoubin Wang, Huan Li, Xiaolong Zhang, Hao Jiang, Lei Shen

    Published 2025-06-01

    The existing multi-carrier composite modulation recognition methods have failed to effectively integrate inner and outer modulation characteristics, thereby limiting the potential for improving recognition performance under low signal-to-noise ratio (SNR) conditions. To address this issue, this pape...

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  3. 3

    Efficient detection of specific volatile organic compounds using functionalized titanium carbide (Ti3C2Tx) MXenes by Narender Kumar, Tanveer Hussain, Lei Shen, Yuan Ping Feng, Nacir Tit

    Published 2025-08-01

    Early diagnosis of cancer is crucially important for prescribing a therapy plan to possibly save human lives. Towards this end, one amongst the pathologies is to consider the efficient detection of volatile organic compounds (VOCs) related, for instance, to the pancreatic cancer existing in exhaled...

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  4. 4
  5. 5

    Multiple-Ring-Core FM-EDF for Weakly-Coupled MDM Amplification With Low Differential Modal Gain by Jinglong Zhu, Mingqing Zuo, Yu Yang, Dawei Ge, Lei Shen, Zhangyuan Chen, Yongqi He, Juhao Li

    Published 2021-01-01

    Recently weakly-coupled mode-division multiplexing (MDM) transmission systems and networks based on ultralow-modal-crosstalk few-mode fiber (FMF) have attracted much interest, for which optical amplification technologies with low modal crosstalk and two-dimension mode-wavelength gain flattening are...

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  6. 6

    Study on Characteristics of Coupled-Core Four-Core Fibers With Different Core Pitches by Junjie Xiong, Lin Ma, Yanming Chang, Tianqi Cheng, Lei Shen, Lei Zhang, Changkun Yan, Lin Sun, Qingwen Liu, Zuyuan He

    Published 2024-01-01

    We studied the characteristics of coupled-core four-core fibers (CC-4CFs) with different core pitches both theoretically and experimentally. The spatial mode dispersions of different fibers were analyzed, and the result agrees well with theoretical ones. In the experiment, we achieved a spatial mode...

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  7. 7

    Glomerular mesangial derived extracellular vesicles deteriorate diabetic kidney disease via miR-3147/PRKAR2B axis by Jiayan Zhang, Fan Zhao, Yiying Tao, Miao Hu, Yujie Bai, Jianzhong Li, Lei Shen, Guoyuan Lu, Zhen Weng, Xiahong Shen, Ling Zhou

    Published 2025-12-01

    To investigate the clinical significance and role of miRNAs with shared patterns in both peripheral blood and kidney tissue-derived extracellular vesicles (EVs) in diabetic kidney disease (DKD). miRNA-Seq was performed on plasma EV samples from DKD and diabetes mellitus (DM) patients, and the valida...

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  8. 8

    First Real-Time 267.8 Tb/S 2 × 70.76 Km Integrated Communication and Sensing Field Trial over Deployed Seven-Core Fiber Cable Using 130 Gbaud PCS-64QAM 1.2 Tb/S OTN Transponders by Jian Cui, Leimin Zhang, Yu Deng, Zhuo Liu, Chao Wu, Bin Hao, Ting Zhang, Yuxiao Wang, Bin Wu, Chengxing Zhang, Yong Chen, Lei Shen, Jie Luo, Yan Sun, Qi Wan, Cheng Chang, Bing Yan, Ninglun Gu

    Published 2025-06-01

    Ultra-high-speed integrated communication and sensing (ICS) transmission techniques are highly desired for next-generation highly reliable optical transport networks (OTNs). The inherent multiple-channel advantage of uncoupled multi-core fibers (MCFs) empowers the evolution of ICS techniques. In thi...

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  9. 9

    Immunomodulatory actions of tonifying polysaccharides: pharmacological effects, mechanisms and therapeutic applications by Jin-Yu Li, Chang Yi, Meng-Qin Zhu, Yan-Feng Yuan, Guang Chen, Ning-Ning Qiu, Lei Shen, Li-Ya Song, Wen-Long Liu, Wen-Long Liu, Wen-Long Liu, Xi-Li Zhang, Xi-Li Zhang

    Published 2025-07-01

    Tonifying polysaccharides, as a class of natural medicines, have attracted considerable interest due to their low toxicity, high safety profile, and excellent stability. Investigations have highlighted the significant impact of polysaccharides derived from Chinese medicinal herbs on the modulation o...

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  10. 10

    Neutralization against Omicron subvariants after BA.5/BF.7 breakthrough infection weakened as virus evolution and aging despite repeated prototype-based vaccination1 by Hongyu Wang, Quanlin Xue, Haocheng Zhang, Guanmin Yuan, Xun Wang, Kai Sheng, Chen Li, Jianpeng Cai, Yuhan Sun, Jingjing Zhao, Jiahuan Lu, Shuyu Fang, Yongfeng Yang, Yeting Zhang, Ying Huang, Jiancui Wang, Jonathan H. Xu, Melissa X. Jiang, Xinyu Wang, Lei Shen, Yuanyuan Liu, Qihui Liu, Qiran Zhang, Sen Wang, Pengfei Wang, Chao Qiu, Jingwen Ai, Wenhong Zhang

    Published 2023-12-01

    Background: Omicron had swept the mainland China between December 2022 and January 2023, while SARS-CoV-2 still continued to evolve. To fully prepare for the next wave, it’s urgent to evaluate the humoral immune response post BA.5/BF.7 breakthrough infection against predominant sub-lineages among ex...

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