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    Methylation profile of individuals with sickle cell trait

    Methylation profile of individuals with sickle cell trait di Ana Gabriela Vasconcelos, Mari Johnson, Yanwei Cai, Li Hsu, Nora Franceschini, Paul L. Auer, Charles Kooperberg, Laura M. Raffield, Alex P. Reiner

    Pubblicazione 2025-12-01

    Sickle cell trait (SCT) is due to heterozygosity for the β-globin sickle cell mutation. SCT recently has been associated with increased risk of various adverse health outcomes. DNA methylation (DNAm) is one potential mechanism by which SCT may impact disease risk. To identify DNAm sites associated w...

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