Search Results - L. R. Pykhova

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  1. 1

    Ultrasound Atherosclerosis Burden Score as a tool for predicting adverse cardiovascular events in patients with various cardiovascular risks aged 40-64 years by V. V. Genkel, A. S. Kuznetcova, L. R. Pykhova, I. I. Shaposhnik

    Published 2022-07-01

    Aim. To investigate the prognostic significance of the Atherosclerosis Burden Score (ABS) in relation to the development of major adverse cardiovascular events in patients of different cardiovascular risks (CVR) aged 40 to 64 years.Material and methods. Men and women aged 40 to 64 years were include...

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  2. 2

    Outcomes of sepsis: a new look at old problems by A. Yu. Savochkina, L. R. Pykhova, O. S. Abramovskikh, E. A. Chetvernina, A. E. Poltorak

    Published 2022-07-01

    Infections represent a common health problem in people at any age. Usually, a local reaction develops in response to the infection, and intensive treatment is not required. However, sometimes the response to infection is inadequate and may lead to organ dysfunction; such condition is defined as sept...

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  3. 3

    Value of duplex ultrasound of carotid and lower extremity arteries in the restratification of cardiovascular risk and initiation of lipid-lowering therapy by V. V. Genkel, A. S. Kuznetsova, L. R. Pykhova, E. V. Lebedev, A. O. Salashenko, I. I. Shaposhnik

    Published 2022-02-01

    Aim. To study the role of duplex ultrasound (DU) of carotid and lower extremity arteries in the restratification of cardiovascular risk (CVR) and changing the indications for lipid-lowering therapy.Material and methods. The study included 291 patients aged 40-64 years without established atheroscler...

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  4. 4

    Abdominal aortic diameter as a predictor of peripheral atherosclerosis progression in 40-64-year-old patients with cardiovascular risk factors by V. V. Genkel, A. S. Kuznetsova, A. I. Dolgushina, A. Yu. Savochkina, K. V. Nikushkina, V. A. Sumerkina, L. R. Pykhova, A. I. Smolensky, I. I. Shaposhnik

    Published 2023-09-01

    Aim. To study the prognostic significance of abdominal aorta (AA) diameter in progression of peripheral atherosclerosis in patients aged 40-64 years and without abdominal aortic dilation.Materials and Methods. The study included 157 outpatients aged 40-64 years who underwent Doppler ultrasonography...

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  5. 5

    Relationships between serum HMGB1 concentration and subpopulation composition of circulating monocytes in patients with subclinical atherosclerosis by V. V. Genkel, I. I. Dolgushin, I. L. Baturina, A. Yu. Savochkina, K. V. Nikushkina, A. A. Minasova, L. R. Pykhova, A. S. Kuznetcova, I. I. Shaposhnik

    Published 2022-07-01

    Chronic non-infectious inflammation of low intensity is the most important mechanism of development and progression in atherosclerosis. Under the conditions of persistent non-resolving inflammation observed in the vascular wall and atherosclerotic plaque (ASB), permanent tissue damage occurs, thus l...

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  6. 6

    Interactions between immunosuppressor neutrophiles, innate and adaptive immunity indexes in the patients with subclinical atherosclerosis by I. I. Dolgushi, V. V. Genkel, I. L. Baturina, A. Yu. Savochkina, A. A. Minasova, K. V. Nikushkina, L. R. Pykhova, A. S. Kuznetcova, I. I. Shaposhnik

    Published 2022-04-01

    The last fifteen years have been marked by rapid progress in the study of neutrophils. The discovery of transcriptional plasticity of neutrophils, their phenotypic and functional heterogeneity contributed to launching active interdisciplinary studies on the role of neutrophils in various chronic inf...

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  7. 7

    Mature neutrophils as a marker of hypoechoic carotid plaques and a predictor of polyvascular disease progression by V. V. Genkel, A. S. Kuznetsova, A. Yu. Savochkina, I. L. Baturina, K. V. Nikushkina, A. A. Minasova, L. R. Pykhova, V. A. Sumerkina, Ya. I. Kudrinskaya, I. I. Shaposhnik, I. I. Dolgushin

    Published 2024-05-01

    Aim. To evaluate the diagnostic and prognostic value of circulating mature and aging neutrophils in relation to hypoechoic carotid plaques and short-term progression of carotid and multifocal atherosclerosis.Material and methods. The study included 200 patients (89 males and 111 fe­males), aged 40-6...

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