Search Results - L. I. Kolesnikova

The paper considers specific features of type 1 Diabetes Mellitus in patients from Buryat populations. Characteristics of the incidence and prevalence of type 1 Diabetes Mellitus in patients of Buryat nationality are presented. Clinicalfeatures of type 1 Diabetes Mellitus in patients-buryats are hig...

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The article presents the study of superoxide dismutase 2 gene polymorphism that plays an important role in antioxidant protection of an organism. We performed genetic typing in representatives of two ethnic groups of Eastern Siberia - Buryats (Mongoloid) and Russians (Caucasoid). Alleles frequencies...

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The article presents the analysis of distribution of alleles and genotypes of AIa16VaI polymorphism (rs4880) of superoxidedismutase 2 (SOD2) gene in Caucasoid teenagers with hypertension (n = 102) and in Caucasoid popuIation sampIing (n = 65), Iiving in the Eastern Siberia. Frequencies of aIIeIes in...

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Oxidative stress plays an important role in the pathogenesis a most of diseases. Important components of protecting cells from oxidative stress are antioxidant enzymes, whose activity is genetically determined, due to the presence in the structure of the alleles of genes. Antioxidant enzymes are cha...

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Significant progress in the field of free radical biology and medicine since the middle of the century has been made. Subsequently, the spectrum of diseases and pathological states believed to be associated with free radicals significantly has been expanded. At present, the development of oxidative...

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The article presents the results of investigation of lipid peroxidation parameters in blood serum and follicile liquid of 78 patients with different IVF results. The increase of lipid peroxidation, products is shown in women with unsuccessful IVF procedure.

Normal lung microbiota is a small number of transient microbes; however, respiratory pathology may be associated with persistent microbial colonization of the lungs. It remains a poorly understood and mysterious part of the pathogenesis of tuberculosis infection.The review considers the general path...

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An analysis of the researches showed that the indigenous ethnic group of Baikal region has high level of adaptation to a place of residence in comparison with migrant. Rate and clinical manifestations of diseases in the Buryat ethnic group have significant differences from the Russian (moderate type...

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Pre-eclampsia is one of the most dangerous complications of pregnancy and increases the risk of adverse outcomes for both mother and fetus. Objective: to study the course of pregnancy, circadian blood pressure profile, autonomic regulation of the heart and metabolic systems in pregnant Buryat women...

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This paper is about 100 years history of the Institute of the epidemiology and microbiology (Irkutsk), development of scientific researches and practical help to the public health.

This review presents data on changes in the physiology of sleep during reproductive aging. It is noted that insomnia and obstructive sleep apnea syndrome (OSAS) are the main sleep disorders. The results of foreign and domestic studies in the field of free radical oxidation during sleep deprivation i...

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The aim of the review is to analyze literature data about sleep homeostasis and the role of the one of circadian system key elements – melatonin – in the regulation of the sleep-wake cycle in women in menopause. It was shown that the prevalence and structure of sleep disorders depends on the menopau...

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The antioxidant system activity was studied in 74 patients undergoing infertility treatment by the vitro fertilization, depending on the effectiveness of the procedure.

In recent years, studies of the human microbiome have led to the development of the gut-brain axis theory, which proposes a relationship between the gut bacterial community and its metabolites and chemical compounds, as well as physiological and pathological processes in the brain. Melatonin is cons...

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Aim. To assess the impact of insertion-deletion polymorphism of apolipoprotein A gene on the development of dyslipidemia among adolescents with essential arterial hypertension (EAH), in regard to the ethnic group: non-indigenous Slavic vs. indigenous Buryat. Material and methods. In total, 399 adole...

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The aim of the study was to assess the functional state of glutathione system in menopausal women of the Buryat ethnic group with insomnia.   Methods. The study involved 94 women aged 45 to 60 years who were divided into perimenopause (n = 44) and postmenopause (n = 50) groups. In each period, a con...

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Purpose: to study nutritional habits as a risk factor of cardiovascular pathology as so as a role of apolipoprotein A1 gene in metabolism in native and alien population of Eastern Siberia. Methods: we used Kiselev questionnaire (1998) for estimation of "nutritional risk". Totally 863 adole...

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Background. Insomnia occurs in more than half of menopausal women. These disorders can contribute to a change in the prooxidant-antioxidant balance, causing the damage to structural cellular elements. Currently, there is a lack of research on this issue.Aim. To carry out a comparative analysis of th...

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Newborn Wistar and August rats (20 rats in each experimental group) were exposed to acute postnatal hypoxic hypoxia (by the mixture of 95% nitrogen and 5% oxygen). Determination of activity of aminolevulinate synthase (ALA-synthase) in bone marrow and liver were in control group, and on the 1st and...

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The literature review examines the problem of obesity in modern society. It has been shown that obesity aggravates concomitant diseases, increases the probability of developing metabolic disorders and related pathologies, increases the risk of complications and mortality. The secretory function of a...

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