Search Results - L. A. Balykova

Aim: to study characteristics of electrophysiological cardiac activity in children of risk groups and to assess possibilities of Holter-electrocardiography (H-ECG) in revealing of cardiac dysfunction during the period of early adaptation. Patients and methods: 250 newborns were examined. The main gr...

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The experience of pneumococcal vaccine usage in the inmates of the Orphanage for Children with Organic Central Nervous System with Psychic Disturbances is discussed in this article. Taking into account the high rate and severe course of acute pneumonia among such children, 120 dosages of pneumococca...

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The emergence of a new variant of the virus and the epidemic potential manifested by the causative agent of COVID-19 have set health professionals tasks related to the rapid development of diagnostics and prevention of a new infection, as well as tactics for providing medical care to patients. The a...

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It is assumed that juvenile idiopathic arthritis (JIA), as many other rheumatic diseases, is in close pathogenic connection with metabolic disorders and early atherosclerosis. However, the prevalence of metabolic syndrome and its components both in healthy Finno-Ugrian children and teens and JIA pat...

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The article presents a case report of aggressive rapidly progressive severe polyarticular juvenile rheumatoid arthritis (JRA) resistant to standard immunosuppressive treatment. Patient with extra-early (up to 6 months) arthritis was successfully treated with genetically engineered biological agent i...

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(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(2):124-125)

The authors represent a review of modern views on abatacept usage in treatment of juvenile idiopathic arthritis emphasizing its high level of safety and possibility to use it in patients resistant to standard basic therapy and tumor necrosis factor alfa inhibitors. The results of clinical investigat...

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The article presents a case of a severe progressive course of a juvenile arthritis refractory to the standard antirheumatic therapy. Due to oligosymptomatic disease onset and low adherence of the patient to treatment, the disease was characterized by development of polyarticular joint syndrome with...

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The article focuses on the modern approaches to evaluation of stress- induced changes in cardiovascular system in young people, regularly participating in sports. The problem of early and achievable diagnostics is highlighted, as by the experience of some abroad experts. Based upon literary data on...

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The article provides information on the unfavourable course of systemic onset juvenile arthritis, resistant to immunosuppressive therapy with methotrexate in combination with cyclosporine, and pulse therapy with methylprednisolone and methotrexate. We describe the successful use of genetically engin...

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Researchers compared efficacy of the conventional therapy (oilment with non steriod anti-inflammatory medication, diclofena sodium and azithromycin) among children with reactive arthritis of Chlamydia etiology and treatment with introduction of gluccosaminilmuramildi peptide and desoxiribonucleate s...

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A short review on modern views on abatacept usage in treatment of juvenile idiopathic arthritis is shown in this article with highlighting of the high safety of this drug in accordance with severe opportunistic infections, including tuberculosis. The authors also discuss possibility of its usage in...

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The article presents a short review of the current notion of the leading role methotrexate in treatment of most clinical variants ofjuvenile idiopathic arthritis. The authors demonstrate that methotrexate is a “gold standard” of antirheumatic therapy and the key disease-modifying drug of pediatric r...

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Our previous studies have demonstrated the importance of early diagnostics and treatment of pathological cardiac transformations in young athletes. The present pilot clinical study is focused on cardioprotective effects of 2-ethyl-6-methyl-3-oxy-pyridine succinate (“Mexicor”, EcoPharmInvest) in youn...

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The aim of the study is to assess the efficacy and safety of the Favipiravir (Areplivir) drug, compared to the standard etiotropic therapy in the patients hospitalized with COVID-19.Material and methods. The research was conducted as a part of an open, randomized, multicenter comparative study of th...

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The authors analyzed NO-synthase expression in white mice exposed to chronic immobilization stress and receiving intraperitoneal 2-ethyl-6-methyl-3-hydroxypyridine succinate (EMHPS). Immune-hystochemical analysis of left ventricular myocardium was performed by standard method, with primary inducible...

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Since the beginning of the pandemic, repeated attempts have been made to develop etiotropic therapy for a novel coronavirus infection. Hydroxychloroquine, lopinavir/ritonavir, etc. derivatives were used as antiviral agents, however, they demonstrated a low efficiency and an insufficient safety. In t...

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Purpose of the study. To evaluate the antitumor efficacy of liposomal doxorubicin hydrochloride in combination with tamoxifen in the treatment of breast cancer.Materials and methods. The study included mongrel white rats (n = 30). A model of carcinogenesis (Walker 256 tumors) was created for all ani...

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In many ways, arterial hypertension and obesity determine the likelihood of a severe course and lethal outcomes in COVID-19. This fact justifies the expediency of an early use of drugs with a direct antiviral action, the analysis of their efficacy not only in the acute, but also in the postcovid per...

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Purpose. To evaluate the regeneration of an infected skin wound in experimental steroid hyperglycemia in rats.Materials and methods. Regeneration of an infected rat skin wound (n = 30) was evaluated on the background of steroid hyperglycemia. Depending on the type of wound surface treatment, all obs...

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