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    The immunomodulatory role of tumor-initiating cells in digestive system tumors: from mechanisms to therapy by Zun-yue Zhang, Zun-yue Zhang, Xin-feng Zhang, Cong-hui Xu, Cong-hui Xu, Kun-hua Wang, Fang Huang

    Published 2025-07-01

    Targeting tumor-initiating cells (TICs) in digestive system tumors is a feasible strategy to boost the effectiveness of cancer immunotherapy. Because of their stem cell-like properties, TICs can cause tumor heterogeneity, recurrence, and resistance to conventional medicines, which can seriously impa...

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