Search Results - Keran Li
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Adeno-Associated Virus Vectors in Retinal Gene Therapy: Challenges, Innovations, and Future Directions
Published 2025-06-01Get full textAdeno-associated virus (AAV) vectors have emerged as the leading platform for retinal gene therapy due to their favorable safety profile, low immunogenicity, and ability to mediate long-term transgene expression within the immune-privileged ocular environment. By integrating diverse strategies such...
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Reprogramming lymphatic endothelial glucose metabolism for the treatment of lymphangiogenesis-related disease
Published 2025-08-01Get full textLymphangiogenesis plays important roles in the pathogenesis of several human diseases, including keratitis, transplant rejection, and cancers. Dysregulated glucose metabolism has emerged as a critical driver of pathological lymphangiogenesis. This study aimed to identify novel regulators of this pro...
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