Search Results - K. A. Zagorodnikova
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The effect of rs776746 polymorphism in the <i>CYP3A5</i> gene on heart rate when using bisoprolol in patients with acute coronary syndrome
Published 2022-09-01Get full textAim. The aim of this work was to study the occurrence of the rs776746 allelic variant of the CYP3A5 gene and its effect on heart rate (HR) when using bisoprolol in patients hospitalized with acute coronary syndrome (ACS).Materials and methods. The study included patients with ACS who were prescribed...
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Clinical and Economic Expedience of Ertapenem Therapy of Complicated Urinary Tract Infection
Published 2020-05-01Get full textClinical and economic investigation of various antibiotics use in the treatment of complicated urinary tract infection (CUTI) was performed under the Russian economic environment. The drugs of comparison were ertapenem, ceftriaxone and levofloxacin. Direct costs and their structure were shown, and t...
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Clinical and economic analysis of drug costs in a general hospital in 2014-2018
Published 2020-02-01Get full textObjectives. To study the structure of drug purchases by a general hospital considering the names and costs of the purchased drugs as well as their current consumption by various clinical departments.Materials and Methods. The drug consumption was analyzed using the ABC/VEN and ATC/DDD methods with a...
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NEW ANTIVIRAL DRUG TRIAZID. RESULTS OF FIRST PHASE OF CLINICAL TRIAL
Published 2019-01-01Get full textThe paper contains а results of the study of the pharmacokinetics, tolerability and safety of a new influenza drug Triazide in several dose regimens conducted on healthy volunteers. The convenient method for the determining the Triazide in blood plasma and urine by the HPLC have been proposed for th...
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Infectious endocarditis and infection of intracardiac devices in adults. Clinical guidelines 2021
Published 2022-11-01Get full text.
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