Søgeresultater - Joshua Peter
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Cell type–dependent role of transforming growth factor-β signaling on postnatal neural stem cell proliferation and migration
Udgivet 2026-03-01Få fuldtekstAdult neurogenesis continuously produces new neurons critical for cognitive plasticity in adult rodents. While it is known transforming growth factor-β signaling is important in embryonic neurogenesis, its role in postnatal neurogenesis remains unclear. In this study, to define the precise role of t...
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Inhibition of PTPRS function does not affect the survival or regeneration of dopaminergic neurons but alters synaptic function in the nigrostriatal pathway
Udgivet 2025-09-01Få fuldtekstParkinson's Disease (PD) is characterized by midbrain dopaminergic (mDA) neuron degeneration in the ventral midbrain, contributing to debilitating motor symptoms. This study investigated whether Protein Tyrosine Phosphatase Receptor Sigma (PTPRS), a known inhibitor of axonal growth through chon...
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Effectiveness of education and training programmes to help clinicians assess and classify perineal tears: a systematic review
Udgivet 2025-06-01Få fuldtekstObjective For every 100 women having a vaginal birth, approximately four will experience a severe (third-degree or fourth-degree) perineal tear. Severe perineal tears are associated with significant short-term and long-term consequences if not recognised and repaired. There are global efforts to red...
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Identifying and assessing the capacity and experience of trial sites in low- and middle-income countries for high-quality randomised drug trials in maternal and perinatal health
Udgivet 2025-07-01Få fuldtekstExisting international consortia for drug trials in maternal and perinatal health have focused largely on pragmatic trials using off-label medicines. This study aimed to identify and assess the capacity and experience of sites in low- and middle-income countries (LMICs) for conducting trials for reg...
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