Search Results - John R. McAnally

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    A mechanistic basis of fast myofiber vulnerability to neuromuscular diseases by Matthieu Dos Santos, Svetlana Bezprozvannaya, John R. McAnally, Chunyu Cai, Ning Liu, Eric N. Olson

    Published 2025-07-01

    Summary: Neuromuscular diseases such as amyotrophic lateral sclerosis and sarcopenia cause muscle atrophy, which preferentially affects fast-twitch glycolytic myofibers. The mechanisms underlying the susceptibility of fast myofibers to disease remain unclear. To investigate this, we analyzed the tra...

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